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Home TrueClone TGFB1 Clone

TGFB1 (NM_000660) Human cDNA Clone

Specifications Citations (5) Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC119746 TGFB1 (untagged)-Human transforming growth factor, beta 1 (TGFB1), NM_000660.3, 10ug $185 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA310081 Rabbit anti-TGFB1 polyclonal antibody, 100ul $325 3 Weeks
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OriGene Data
Vector:pCMV6-XL4 Insert Size: 1870 Restriction Site: NotI-NotI
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence          3' Read Nucleotide Sequence         
OTI Annotation: TRueClone
OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Secreted ProteinES Cell Differentiation/IPSTranscription FactorsDruggable Genome
Protein Pathways: MAPK signaling pathwayCytokine-cytokine receptor interactionCell cycleTGF-beta signaling pathwayPathways in cancerColorectal cancerMore Pathways >>
Reference Data
RefSeq: NM_000660.3, NP_000651
RefSeq Size: 2346 RefSeq ORF: 1173
Synonyms : CED; DPD1; LAP; TGFB; TGFbeta
LocusID: 7040 Cytogenetic: 19q13.1 Domains: TGFb_propeptide, TGF-beta
Summary: This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.[provided by RefSeq, Oct 2009].

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping


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