Ceramide glucosyltransferase (UGCG) Human Gene Knockout Kit (CRISPR)

CAT#: KN206288BN

UGCG - human gene knockout kit via CRISPR, HDR mediated

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
• Donor DNA: mBFP-Neo
• Symbol: Ceramide glucosyltransferase
• Locus ID: 7357
• Components:

  KN206288G1, Ceramide glucosyltransferase gRNA vector 1 in pCas-Guide CRISPR vector

  KN206288G2, Ceramide glucosyltransferase gRNA vector 2 in pCas-Guide CRISPR vector

  KN206288BND, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

  GE100003, scramble sequence in pCas-Guide vector

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_003358
• UniProt ID: Q16739
• Synonyms: GCS; GLCT1
• Summary: This gene encodes an enzyme that catalyzes the first glycosylation step in the biosynthesis of glycosphingolipids, which are membrane components containing lipid and sugar moieties. The product of this reaction is glucosylceramide, which is the core structure of many glycosphingolipids. [provided by RefSeq, Dec 2014]