Human KLF2 activation kit by CRISPRa

CAT#: GA107062

KLF2 CRISPRa kit - CRISPR gene activation of human Kruppel like factor 2

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: KLF2
• Locus ID: 10365
• Kit Components:

  GA107062G1, KLF2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA107062G2, KLF2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA107062G3, KLF2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_016270
• UniProt ID: Q9Y5W3
• Synonyms: LKLF
• Summary: This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is expressed early in mammalian development and is found in many different cell types. The protein acts to bind the CACCC box found in the promoter of target genes to activate their transcription. It plays a role in many processes during development and disease including adipogenesis, embryonic erythropoiesis, epithelial integrity, inflammation and t-cell viability. [provided by RefSeq, Mar 2017]