Human RHEB activation kit by CRISPRa

CAT#: GA104102

RHEB CRISPRa kit - CRISPR gene activation of human Ras homolog, mTORC1 binding

Product Images

Specifications

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Symbol: RHEB
• Locus ID: 6009
• Kit Components:

  GA104102G1, RHEB gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104102G2, RHEB gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104102G3, RHEB gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005614
• UniProt ID: Q15382
• Synonyms: RHEB2
• Summary: This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22. [provided by RefSeq, Jul 2008]