MERTK (NM_006343) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC215289L3V

Lenti ORF particles, MERTK (Myc-DDK-tagged)-Human c-mer proto-oncogene tyrosine kinase (MERTK), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: MERTK
• Synonyms: c-Eyk; c-mer; MER; RP38; Tyro12
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_006343
• ORF Size: 2997 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC215289).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_006343.2
• RefSeq Size: 3632 bp
• RefSeq ORF: 3000 bp
• Locus ID: 10461
• UniProt ID: Q12866
• Cytogenetics: 2q13
• Domains: pkinase, TyrKc, S_TKc, ig, IG, FN3
• Protein Families: Druggable Genome, Protein Kinase, Transmembrane
• MW: 110.25 kDa
• Gene Summary: This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq, Jul 2008]