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CDC25B (NM_021873) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC207409L4V
- LentiORF®
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Lenti ORF particles, CDC25B (mGFP-tagged) - Human cell division cycle 25 homolog B (S. pombe) (CDC25B), transcript variant 1, 200ul, >10^7 TU/mL
Lentiviral Particles: DDK DDK w/ Puro mGFP
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USD 365.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone Lentiviral Particle |
| Tag | mGFP |
| Symbol | CDC25B |
| Mammalian Cell Selection | Puromycin |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_021873 |
| ORF Size | 1740 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC207409).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_021873.2 |
| RefSeq Size | 3696 bp |
| RefSeq ORF | 1743 bp |
| Locus ID | 994 |
| UniProt ID | P30305 |
| Cytogenetics | 20p13 |
| Domains | RHOD |
| Protein Families | Druggable Genome, Phosphatase |
| Protein Pathways | Cell cycle, MAPK signaling pathway, Progesterone-mediated oocyte maturation |
| MW | 65 kDa |
| Gene Summary | CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. [provided by RefSeq, Jul 2008] |
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