Fscn1 (NM_007984) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR207918L4V

Lenti ORF particles, Fscn1 (GFP-tagged) - Mouse fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus) (Fscn1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Mouse Tagged ORF Clone
• Tag: mGFP
• Symbol: Fscn1
• Synonyms: AI663989; Fan1; fascin-1
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_007984
• ORF Size: 1479 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR207918).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_007984.2, NP_032010.2
• RefSeq Size: 2667 bp
• RefSeq ORF: 1482 bp
• Locus ID: 14086
• UniProt ID: Q61553
• Cytogenetics: 5 81.84 cM
• Gene Summary: Actin-binding protein that contains 2 major actin binding sites (By similarity). Organizes filamentous actin into parallel bundles (PubMed:7738015). Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers (By similarity). Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration (PubMed:21685497). Mediates reorganization of the actin cytoskeleton and axon growth cone collapse in response to NGF (By similarity).[UniProtKB/Swiss-Prot Function]