PALB2 (NM_024675) Human Untagged Clone

CAT#: SC322638

PALB2 (untagged)-Human partner and localizer of BRCA2 (PALB2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PALB2
• Synonyms: FANCN; PNCA3
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322638 CTGAGGGTGCGATCCCGGGCTCCCCATTCCTTCCTGGGGCGCCTCCCCGGCCCAGGGCCA
  ACTGGGTCCCGGTGTCGGCAGGCCTGGGGTCGGCGACGGCTGCTCTTTTCGTTCTGTCGC
  CTGCCCGATGGACGAGCCTCCCGGGAAGCCCCTCAGCTGTGAGGAGAAGGAAAAGTTAAA
  GGAGAAATTAGCATTCTTGAAAAGGGAATACAGCAAGACACTAGCCCGCCTTCAGCGTGC
  CCAAAGAGCTGAAAAGATTAAGCATTCTATTAAGAAAACAGTAGAAGAACAAGATTGTTT
  GTCTCAGCAGGATCTCTCACCGCAGCTAAAACACTCAGAACCTAAAAATAAAATATGTGT
  TTATGACAAGTTACACATCAAAACCCATCTTGATGAAGAAACTGGAGAAAAGACATCTAT
  CACACTTGATGTTGGGCCTGAGTCCTTTAACCCTGGAGATGGCCCAGGAGGATTACCTAT
  ACAAAGAACAGATGACACCCAAGAACATTTTCCCCACAGGGTCAGTGACCCTAGTGGTGA
  GCAAAAGCAGAAGCTGCCAAGCAGAAGAAAGAAGCAGCAGAAGAGGACATTTATTTCACA
  GGAGAGAGACTGTGTCTTTGGCACTGATTCACTCAGATTGTCTGGGAAAAGACTAAAGGA
  ACAGGAAGAAATCAGTAGCAAAAATCCTGCTAGATCACCAGTAACTGAAATAAGAACTCA
  CCTTTTAAGTCTTAAATCTGAACTTCCAGATTCTCCAGAACCAGTTACAGAAATTAATGA
  AGACAGTGTATTAATTCCACCAACTGCCCAACCAGAAAAAGGTGTTGATACATTCCTAAG
  AAGACCTAATTTCACCAGGGCGACTACAGTTCCTTTACAGACTCTATCAGATAGCGGTAG
  TAGTCAGCACCTTGAACACATTCCTCCTAAAGGTAGCAGTGAACTTACTACTCACGACCT
  AAAAAACATTAGATTTACTTCACCTGTAAGTTTGGAGGCACAAGGCAAAAAAATGACTGT
  CTCTACAGATAACCTCCTTGTAAATAAAGCTATAAGTAAAAGTGGCCAACTGCCCACAAG
  TTCTAATTTAGAGGCAAATATTTCATGTTCTCTAAATGAACTCACCTACAATAACTTACC
  AGCAAATGAAAACCAAAACTTAAAAGAACAAAATCAAACAGAGAAATCTTTAAAATCTCC
  CAGTGACACTCTTGATGGCAGGAATGAAAATCTTCAGGAAAGTGAGATTCTAAGTCAACC
  TAAGAGTCTTAGCCTGGAAGCAACCTCTCCTCTTTCTGCAGAAAAACATTCTTGCACAGT
  GCCTGAAGGCCTTCTGTTTCCTGCAGAATATTATGTTAGAACAACACGAAGCATGTCCAA
  TTGCCAGAGGAAAGTAGCCGTGGAGGCTGTCATTCAGAGTCATTTGGATGTCAAGAAAAA
  AGGGTTTAAAAATAAAAATAAGGATGCAAGTAAAAATTTAAACCTTTCCAATGAGGAAAC
  TGACCAAAGTGAAATTAGGATGTCTGGCACATGCACAGGACAACCAAGTTCAAGAACCTC
  TCAGAAACTTCTCTCATTAACTAAAGTCAGCTCTCCCGCTGGGCCCACTGAAGATAATGA
  CTTGTCTAGGAAGGCAGTTGCCCAAGCACCTGGTAGAAGATACACAGGAAAAAGAAAATC
  AGCCTGCACCCCAGCATCAGATCATTGTGAACCACTTTTGCCAACTTCTAGCCTGTCGAT
  TGTTAACAGGTCCAAGGAAGAAGTCACCTCACACAAATATCAGCACGAAAAATTATTTAT
  TCAAGTGAAAGGGAAGAAAAGTCGTCATCAAAAAGAGGATTCCCTTTCTTGGAGTAATAG
  TGCTTATTTATCCTTGGATGATGATGCTTTCACGGCTCCATTTCATAGGGATGGAATGCT
  GAGTTTAAAGCAACTACTGTCTTTTCTCAGTATCACAGACTTTCAGTTACCTGATGAAGA
  CTTTGGACCTCTTAAGCTTGAAAAAGTGAAGTCCTGCTCAGAAAAACCAGTGGAGCCCTT
  TGAGTCAAAAATGTTTGGAGAGAGACATCTTAAAGAGGGAAGCTGTATTTTTCCAGAGGA
  ACTGAGTCCTAAACGCATGGATACAGAAATGGAGGACTTAGAAGAGGACCTTATTGTTCT
  ACCAGGAAAATCACATCCCAAAAGGCCAAACTCGCAAAGCCAGCATACAAAGACGGGCCT
  TTCTTCATCCATATTACTTTATACTCCTTTAAATACGGTTGCGCCTGATGATAATGACAG
  GCCTACCACAGACATGTGTTCACCTGCTTTCCCCATCTTAGGTACTACTCCAGCCTTTGG
  CCCTCAAGGCTCCTATGAAAAAGCATCTACAGAAGTTGCTGGACGAACTTGCTGCACACC
  CCAACTTGCTCATTTGAAAGACTCAGTCTGTCTTGCCAGTGATACTAAACAATTCGACAG
  TTCAGGCAGCCCAGCAAAACCACATACCACCCTGCAAGTGTCAGGCAGGCAAGGACAACC
  TACCTGTGACTGTGACTCTGTCCCGCCAGGAACACCTCCACCCATTGAGTCATTCACTTT
  TAAAGAAAATCAGCTCTGTAGAAACACATGCCAGGAGCTGCATAAACATTCCGTCGAACA
  GACTGAAACAGCAGAGCTTCCTGCTTCTGATAGCATAAACCCAGGCAACCTACAATTGGT
  TTCAGAGTTAAAGAATCCTTCAGGTTCCTGTTCCGTAGATGTGAGTGCCATGTTTTGGGA
  AAGAGCCGGTTGTAAAGAGCCATGTATCATAACTGCTTGCGAAGATGTAGTTTCTCTTTG
  GAAAGCTCTGGATGCTTGGCAGTGGGAAAAACTTTATACCTGGCACTTCGCAGAGGTTCC
  AGTATTACAGATAGTTCCAGTGCCTGATGTGTATAATCTCGTGTGTGTAGCTTTGGGAAA
  TTTGGAAATCAGAGAGATCAGGGCATTGTTTTGTTCCTCTGATGATGAAAGTGAAAAGCA
  AGTACTACTGAAGTCTGGAAATATAAAAGCTGTGCTTGGCCTGACAAAGAGGAGGCTAGT
  TAGTAGCAGTGGGACCCTTTCTGATCAACAAGTAGAAGTCATGACGTTTGCAGAAGATGG
  AGGAGGCAAAGAAAACCAATTTTTGATGCCCCCTGAGGAGACTATACTAACTTTTGCTGA
  GGTCCAAGGGATGCAAGAAGCTCTGCTTGGTACTACTATTATGAACAACATTGTTATTTG
  GAATTTAAAAACTGGTCAACTCCTGAAAAAGATGCACATTGATGATTCTTACCAAGCTTC
  AGTCTGTCACAAAGCCTATTCTGAAATGGGGCTTCTCTTTATTGTCCTGAGTCATCCCTG
  TGCCAAAGAGAGTGAGTCGTTGCGAAGCCCTGTGTTTCAGCTCATTGTGATTAACCCTAA
  GACGACTCTCAGCGTGGGTGTGATGCTGTACTGTCTTCCTCCAGGGCAGGCTGGCAGGTT
  CCTGGAAGGTGACGTGAAAGATCACTGTGCAGCAGCAATCTTGACTTCTGGAACAATTGC
  CATTTGGGACTTACTTCTCGGTCAGTGTACTGCCCTCCTCCCACCTGTCTCTGACCAACA
  TTGGTCTTTTGTGAAATGGTCGGGTACAGACTCTCATTTGCTGGCTGGACAAAAAGATGG
  AAATATATTTGTATACCACTATTCATAAGTTAGGGTAAAGTGAAAACACAATTTTCTGGA
  TATATTGGGCCTCTTAGTATTTTTTGGAGTTTTAAATATAAAGGAGAATATCTGAATGAC
  ACTTAAAATGATTGCTTGTTTATGTCCAGACAGACTTATTTTTTATTCTAATGATGGTAG
  CACCACTGATCTTGGATGTACATTTATGTATACTTTGAGAAAAAGGGTTTTAGGTTGATT
  TTTGTAATTTCCCACATTTGTACATGTGCTTTTAAAGGTGTACATAAAGCTTCAAATGGC
  AATAAATATTTATTTTTATAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_024675
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_024675.3, NP_078951.2
• RefSeq Size: 4069 bp
• RefSeq ORF: 3561 bp
• Locus ID: 79728
• UniProt ID: Q86YC2
• Cytogenetics: 16p12.2
• Gene Summary: This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the stable intranuclear localization and accumulation of BRCA2. [provided by RefSeq, Jul 2008]