Macrophage Inflammatory Protein 3 beta (CCL19) (NM_006274) Human Untagged Clone

CAT#: SC122744

CCL19 (untagged)-Human chemokine (C-C motif) ligand 19 (CCL19)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: Macrophage Inflammatory Protein 3 beta
• Synonyms: CKb11; ELC; MIP-3b; MIP3B; SCYA19
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_006274 edited
  CATCACTCACACCTTGCATTTCACCCCTGCATCCCAGTCGCCCTGCAGCCTCACACAGAT
  CCTGCACACACCCAGACAGCTGGCGCTCACACATTCACCGTTGGCCTGCCTCTGTTCACC
  CTCCATGGCCCTGCTACTGGCCCTCAGCCTGCTGGTTCTCTGGACTTCCCCAGCCCCAAC
  TCTGAGTGGCACCAATGATGCTGAAGACTGCTGCCTGTCTGTGACCCAGAAACCCATCCC
  TGGGTACATCGTGAGGAACTTCCACTACCTTCTCATCAAGGATGGCTGCAGGGTGCCTGC
  TGTAGTGTTCACCACACTGAGGGGCCGCCAGCTCTGTGCACCCCCAGACCAGCCCTGGGT
  AGAACGCATCATCCAGAGACTGCAGAGGACCTCAGCCAAGATGAAGCGCCGCAGCAGTTA
  ACCTATGACCGTGCAGAGGGAGCCCGGAGTCCGAGTCAAGCATTGTGAATTATTACCTAA
  CCTGGGGAACCGAGGACCAGAAGGAAGGACCAGGCTTCCAGCTCCTCTGCACCAGACCTG
  ACCAGCCAGGACAGGGCCTGGGGTGTGTGTGAGTGTGAGTGTGAGCGAGAGGGTGAGTGT
  GGTCAGAGTAAAGCTGCTCCACCCCCAGATTGCAATGCTACCAATAAAGCCGCCTGGTGT
  TTACAACTAAAAAAAAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006274 unedited
  AGGGCGGCACACCCATTCCCGGGCTACATCACTCACACCTTGCATTTCACCCCTGCATCC
  CAGTCGCCCTGCAGCCTCACACAGATCCTGCACACACCCAGACAGCTGGCGCTCACACAT
  TCACCGTTGGCCTGCCTCTGTTCACCCTCCATGGCCCTGCTACTGGCCCTCAGCCTGCTG
  GTTCTCTGGTACTTCCCCAGCCCCAACTCTGAGTGGCACCAATGATGCTGAAGACTGCTG
  CCTGTCTGTGACCCAGAAACCCATCCCTGGGTACATCGTGAGGAACTTCCACTACCTTCT
  CATCAAGGATGGCTGCAGGGTGCCTGCTGTAGTGTTCACCACACTGAGGGGCCGCCAGCT
  CTGTGCACCCCCAGACCAGCCCTGGGTAGAACGCATCATCCAGAGACTGCAGAGGACCTC
  AGCCAAGATGAAGCGCCGCAGCAGTTAACCTATGACCGTGCAGAGGGAGCCCGGAGTCCG
  AGTCAAGCATTGTGAATTATTACCTAACCTGGGGAACCGAGGACCAGAAGGAAGGACCAG
  GCTTCCAGCTCCTCTGCACCAGACCTGACCAGCCAGGACAGGGCCTGGGGTGTGTGTGAG
  TGTGAGTGTGAGCGAGAGGGTGAGTGTGGTCAGAGTAAAGCTGCTCCACCCCCAGATTGC
  AATGCTACCAATAAAGCCGCCTGGTGTTTACAACTAANAAAAANNNNNNNAANNNNANNN
  NGGGCGGCCGCGGTCATAGCTGTTTCCTGAACAGATCCCGGGTGGCATCCCTGTGACCCC
  TCCCCGTGCCTCTCCTGGCCCTGGNAAGTGCCACTCCAGTGCCCACCAGCCTTGTCCTAT
  AAAATTAAGTGC
  
• Restriction Sites: Please inquire
• ACCN: NM_006274
• Insert Size: 694 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_006274.2, NP_006265.1
• RefSeq Size: 684 bp
• RefSeq ORF: 297 bp
• Locus ID: 6363
• UniProt ID: Q99731
• Cytogenetics: 9p13.3
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Chemokine signaling pathway, Cytokine-cytokine receptor interaction
• Gene Summary: This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene may play a role in normal lymphocyte recirculation and homing. It also plays an important role in trafficking of T cells in thymus, and in T cell and B cell migration to secondary lymphoid organs. It specifically binds to chemokine receptor CCR7. [provided by RefSeq, Sep 2014]