ZGPAT Rabbit Polyclonal Antibody

CAT#: TA370226

ZGPAT rabbit polyclonal antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane 1-4: Human fetal liver tissue LO2 cell PC-3 cell HEPG2 cell lysates Primary antibody: TA370226 (ZGPAT Antibody) at dilution 1/400 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 2 minutes

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  Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TA370226 (ZGPAT Antibody) at dilution 1/55 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TA370226 (ZGPAT Antibody) at dilution 1/55, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA370226 (ZGPAT Antibody) at dilution 1/55 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA370226 (ZGPAT Antibody) at dilution 1/55, treated with fusion protein. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Human fetal liver tissue, LO2 cell, PC-3 cell, HEPG2 cell lysates
  IHC: 50-300
  Positive control: Human ovarian cancer
  Predicted cell location: Nucleus
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human ZGPAT
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 57 kDa
• Gene Name: zinc finger CCCH-type and G-patch domain containing
• Database Link:
  Entrez Gene 84619 Human
  UniProt ID Q8N5A5
• Background: Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis.
• Synonyms: dJ583P15.3; FLJ14972; GPATC6; GPATCH6; KIAA1847; MGC44880; ZC3H9; ZC3HDC9; ZIP