AZI2 Rabbit Polyclonal Antibody

CAT#: TA347658

Rabbit Polyclonal Anti-AZI2 Antibody

Product Images

Western blot analysis on HepG2 cell lysate using AZI2 Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-AZI2 Antibody: A synthesized peptide derived from human AZI2
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 48 kDa
• Gene Name: 5-azacytidine induced 2
• Database Link:
  NP_071906
  Entrez Gene 27215 MouseEntrez Gene 316051 RatEntrez Gene 64343 Human
  UniProt ID Q9H6S1
• Background: AZI2 Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFN-beta promoter activation via TICAM1. Interacts with IKBKE, TBK1 and TICAM1. 2 isoforms of the human protein are produced by alternative splicing.
• Synonyms: AZ2; NAP1; TILP
• Note: AZI2 Antibody detects endogenous levels of AZI2

Reference Data

• Protein Pathways: RIG-I-like receptor signaling pathway