SUMO4 Rabbit Polyclonal Antibody

CAT#: TA327517

SUMO4 Rabbit Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using SUMO4 antibody.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1:1000-1:2000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide of human SUMO4
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: small ubiquitin-like modifier 4
• Database Link:
  NP_001002255
  Entrez Gene 387082 Human
  UniProt ID Q6EEV6
• Background: This gene is a member of the SUMO gene family. This family of genes encode small ubiquitin-related modifiers that are attached to proteins and control the target proteins subcellular localization, stability, or activity. The protein described in this record is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene. A specific polymorphism in this SUMO gene, which leads to the M55V substitution, has been associated with type I diabetes. The RefSeq contains this polymorphism.
• Synonyms: dJ281H8.4; IDDM5; SMT3H4; SUMO-4