TBC1D4 Rabbit Polyclonal Antibody

CAT#: TA319796

Rabbit Polyclonal TBC1D4 Antibody

Product Images

Immunohistochemistry of TBC1D4 in human prostate tissue with TBC1D4 antibody at 10 ug/mL.

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: ICC: 10 ug/mL
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: TBC1D4 antibody was raised against an 19 amino acid peptide near the carboxy terminus of human TBC1D4 .
• Formulation: TBC1D4 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: TBC1D4 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 143 kDa; Observed: 140 kDa
• Gene Name: TBC1 domain family member 4
• Database Link:
  NP_055647
  Entrez Gene 9882 Human
  UniProt ID O60343
• Background: TBC1D4 Antibody: TBC1D4, also known as the Akt substrate AS160, was initially identified as an Akt substrate containing a GTPase-activating domain that regulates GLUT4 trafficking, with activation following insulin stimulation. TBC1D4 truncations in humans is a major cause of dominant inherited insulin resistance. The loss of TBC1D4 results in the accumulation of GLUT4 in compartments that are primed for fusion in basal adipocytes.
• Synonyms: AS160; NIDDM5