GRAP Rabbit Polyclonal Antibody

CAT#: TA308618

Rabbit Polyclonal antibody to GRAP (GRB2-related adaptor protein)

Product Images

Sample (30 ug of whole cell lysate). A: A549 12% SDS PAGE. TA308618 diluted at 1:1000.

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  Immunohistochemical analysis of paraffin-embedded U373 xenograft, using GRAP (TA308618) antibody at 1:100 dilution.

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  Immunofluorescence analysis of methanol-fixed A549, using GRAP (TA308618) antibody at 1:500 dilution.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human (Predicted: Rat, Bovine, Rhesus Monkey, Mouse)
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region within amino acids 155 and 217 of GRAP (Uniprot ID#Q13588)
• Formulation: 1XPBS, 40% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 25 kDa
• Gene Name: GRB2-related adaptor protein
• Database Link:
  NP_006604
  Entrez Gene 71520 MouseEntrez Gene 363616 RatEntrez Gene 10750 Human
  UniProt ID Q13588
• Background: This gene encodes a member of the GRB2/Sem5/Drk family. This member functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. [provided by RefSeq]
• Synonyms: MGC64880
• Note: Seq homology of immunogen across species: Mouse (100%), Rat (100%), Rhesus Monkey (100%), Bovine (92%)