SUOX Rabbit Polyclonal Antibody

CAT#: TA308158

Rabbit Polyclonal antibody to SUOX (sulfite oxidase)

Product Images

Sample (50 ug of whole cell lysate). A: mouse liver. 7.5% SDS PAGE. TA308158 diluted at 1:1000.

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  Sample (30 ug whole cell lysate). A:Hep G2. 7.5% SDS PAGE. TA308158 diluted at 1:500

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  Immunohistochemical analysis of paraffin-embedded OVCA xenograft, using SUOX (TA308158) antibody at 1:100 dilution.

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  Immunofluorescence analysis of methanol-fixed HepG2, using SUOX (TA308158) antibody at 1:200 dilution.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human, Mouse (Predicted: Pig, Rat, Bovine)
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 291 of SUOX (Uniprot ID#P51687)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 60 kDa
• Gene Name: sulfite oxidase
• Database Link:
  NP_001027559
  Entrez Gene 81805 RatEntrez Gene 211389 MouseEntrez Gene 6821 Human
  UniProt ID P51687
• Background: Sulfite oxidase is a homodimeric protein localized to the intermembrane space of mitochondria. Each subunit contains a heme domain and a molybdopterin-binding domain. The enzyme catalyzes the oxidation of sulfite to sulfate, the final reaction in the oxidative degradation of the sulfur amino acids cysteine and methionine. Sulfite oxidase deficiency results in neurological abnormalities which are often fatal at an early age. Alternative splicing results in multiple transcript variants encoding identical proteins. [provided by RefSeq]
• Synonyms: OTTHUMP00000158619; sulfite oxidase
• Note: Seq homology of immunogen across species: Pig (86%), Rat (82%), Bovine (82%)

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Sulfur metabolism