Pirin (PIR) Goat Polyclonal Antibody

CAT#: TA302574

Goat Polyclonal Antibody against Pirin

Product Images

TA302574 (0.3ug/ml) staining of Human Heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1:128,000. WB: 0.3 - 1.0 µg/ml.
• Reactivities: Human (Expected from sequence similarity: Mouse)
• Host: Goat
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Peptide with sequence GSSKKVTLSVLSREC, from the N Terminus of the protein sequence according to NP_003653.
• Formulation: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Concentration: lot specific
• Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 35738 Da
• Gene Name: pirin
• Database Link:
  NP_003653
  Entrez Gene 69656 MouseEntrez Gene 8544 Human
  UniProt ID O00625
• Background: This gene encodes a member of the cupin superfamily. The encoded protein is an Fe(II)-containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor as well as B cell lymphoma 3-encoded oncoprotein suggest the encoded protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication. Alternatively spliced transcript variants have been described.
• Synonyms: OTTHUMP00000022961; OTTHUMP00000022962; pirin; pirin (iron-binding nuclear protein)

Reference Data

• Protein Families: Transcription Factors