Neurotrophin 3 (NTF3) Rabbit Polyclonal Antibody

CAT#: AP23334PU-N

Neurotrophin 3 (NTF3) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of rat brain tissue lysis using NT3 antibody

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  Immunohistochemical analysis of paraffin embedded rat tissue sections (brain) using NT3 antibody

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western blot: Use at 1-2 μg/ml with the appropriate system to detect NT-3 in cells and tissues.
  Immunohistochemistry on Paraffin Sections: Use at 0.5-1 μg/ml to detect NT-3in formalin fixed and paraffin embedded tissues.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide mapping at the middle region of Human Neurotrophin-3
• Specificity: This antibody detects Neurotrophin 3 / NTF3 in the middle.
• Formulation: 50% Glycerol, 0.9mg NaCl, 0.2mg Na2HPO4
  State: Aff - Purified
  State: Lyphilized purified Ig fraction
• Reconstitution Method: Restore with 1.2% Sodium Acetate or neutral PBS.
• Concentration: 0.1 mg/ml (after reconstitution with 0.5 ml PBS)
• Purification: Immunoaffinity Chromatography
• Conjugation: Unconjugated
• Storage: Prior to reconstitution store at -20°C.
  Following reconstitution store undiluted at 2-8°C for 3 months
  or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: neurotrophin 3
• Database Link:
  Entrez Gene 18205 MouseEntrez Gene 81737 RatEntrez Gene 4908 Human
  UniProt ID P20783
• Background: Neurotrophin-3 is a member of a family of neurotrophic factors, that is closely related to both nerve growth factor and brain derived neurotrophic factor. These proteins are involved in the maintenance of the adult nervous system and affect development of neurons in the embryo when it is expressed in human placenta. NT3 deficient mice generated by gene targeting display severe movement defects of the limbs.
• Synonyms: Neurotrophin-3, NT-3, Neurotrophic factor, HDNF, Nerve growth factor 2, NGF-2

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: MAPK signaling pathway, Neurotrophin signaling pathway