Collagen IV (COL4A2) Rabbit Polyclonal Antibody

CAT#: AP20477PU-N

Collagen IV (COL4A2) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of COL4A2 antibody (Cat.-No.: AP20477PU-N) in extracts from Jurkat cells.

• 

  Immunohistochemistry (IHC) analyzes of COL4A2 antibody (Cat.-No.: AP20477PU-N) in paraffin-embedded human colon carcinoma tissue.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: Western Blot: 1/500 - 1/1000.
  Immunohistochemistry on paraffin sections: 1/50 - 1/200.
  Immunofluorescence: 1/50 - 1/200.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of COL4A2 protein.
  (region surrounding Pro175)
• Formulation: PBS, pH 7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.02% sodium azide, 50% glycerol
• Concentration: 1.0 mg/ml
• Purification: Affinity chromatography (> 95% (by SDS-PAGE)
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~150 kDa
• Gene Name: collagen type IV alpha 2
• Database Link:
  Entrez Gene 1284 Human
  UniProt ID P08572
• Background: The extensive family of COL gene products (collagens) is composed of several chain types, including fibril-forming interstitial collagens (Types I, II, III and V) and basement membrane collagens (Type IV), each type containing multiple isoforms. Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. Several collagens also play a role in cell adhesion, important for maintaining normal tissue architecture and function.
• Synonyms: COL4A2

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: ECM-receptor interaction, Focal adhesion, Pathways in cancer, Small cell lung cancer