Ppard (N-term) Rabbit Polyclonal Antibody

CAT#: AP05660PU-N

Ppard (N-term) rabbit polyclonal antibody, Purified

Specifications

Product Data

• Applications: ELISA, WB
• Recommended Dilution: ELISA: 1:2000 - 1:8000.
  Western Blot: 1:500 - 1:2000; detects a band of approximately 55kDa in heart whole cell lysates.
• Reactivities: Human, Monkey, Mouse, Rabbit, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Syntetic peptide corresponding to amino acids 1-14 of mouse PPAR delta.
• Specificity: This antibody detects peroxisome proliferator-activated receptor, delta (PPARD).
• Formulation: Phosphate buffered saline pH7.2 containing 0.01% Sodium Azide (NaN3)
  State: Purified
  State: Liquid purified IgG
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: peroxisome proliferator activator receptor delta
• Database Link:
  Entrez Gene 5467 HumanEntrez Gene 25682 RatEntrez Gene 19015 Mouse
  UniProt ID P35396
• Background: PPARD is a member of the nuclear hormone receptor subfamily. Upon activation, PPARD forms heterodimers with retinoid X receptors (RXRs), and functions to regulate transcription of specific gene sequences. PPARD controls genes involved in lipid metabolism, and enhances fatty acid catabolism and energy uncoupling in adipose tissue and skeletal muscle. PPARD has also been implicated in the proliferation and differentiation of preadipocytes, enterocytes, keratinocytes and the placenta.
  PPARD agonists could be used therapeutically to target multiple components of the metabolic syndrome, including insulin resistance, hyperglycemia, dyslipidemia, and atherosclerosis.
• Synonyms: PPAR-beta, Nuclear hormone receptor 1, NUCI, PPARD, NR1C2, PPARB