TIM 1 (HAVCR1) Rabbit Polyclonal Antibody

CAT#: AP05601PU-N

TIM 1 (HAVCR1) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of human uterine lysate probed with Rabbit anti Human TIM-1 at 1 (A) and 2 (B) ug/ml.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1.0 - 2.0 µg/ml; detects a band of approximately 49kDa in human uterus tissue lysate.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: 16 amino acid peptide sequence near the centre of human TIM-1.
• Specificity: This antibody detects T cell immunoglobulin mucin-1 (TIM-1), which was first identified as the receptor used by hepatitis A for viral entry (it is also known as the hepatitis A virus cellular receptor- HAVCR).
• Formulation: Phosphate buffered saline containing 0.02% Sodium Azide
  State: Purified
  State: Liquid purified IgG
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for up to one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: hepatitis A virus cellular receptor 1
• Database Link:
  Entrez Gene 26762 Human
  UniProt ID Q96D42
• Background: TIM-1 is a key cell surface protein that binds TIM-4, leading to T cell proliferation and T helper type 2 (Th2) cytokine production. TIM-1 has also been shown to bind and activate macrophages.
  Two splice variants for human TIM-1 exist; TIM-1a is predominantly expressed in the liver, whilst TIM-1b is expressed in the kidney. Expression of TIM-1 in the kidney is thought to be upregulated in damaged tissue, and is thought to assist healing.
  TIM-1 polymorphisms are associated with asthma.
• Synonyms: TIMD-1, TIM1, TIM-1, T cell membrane protein 1, HAVCR-1