DOK1 Rabbit Polyclonal Antibody
Other products for "DOK1"
Specifications
Product Data | |
Applications | IF, IHC, WB |
Recommended Dilution | Western blot: 1/500 - 1/1000. Immunofluorescence: 1/100 - 1/200. Immunohistochemistry on Paraffin-Embedded Sections: 1/50 - 1/100. |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | The antiserum was produced against synthesized non-phosphopeptide derived from human p62Dok around the phosphorylation site of tyrosine 398 (E-G-Yp-E-L). |
Specificity | This antibody detects endogenous levels of total p62Dok protein. |
Formulation | PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide and 50% Glycerol. State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Affinity chromatography |
Conjugation | Unconjugated |
Storage | Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing. |
Stability | Shelf life: One year from despatch. |
Gene Name | docking protein 1 |
Database Link | |
Background | DOK1 (Downstream of tyrosine kinase 1, or Docking protein 1) is believed to be a mainly cytoplasmic adaptor protein which down-regulates mitogen-activated protein kinase activation, inhibits cell proliferation and transformation, and promotes cell spreading and cell migration. DOK1 appears to be a negative regulator of the insulin signaling pathway. |
Synonyms | Docking protein 1, pp62, p62(dok) |
Reference Data |
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.