alpha 1 Antitrypsin (SERPINA1) Mouse Monoclonal Antibody [Clone ID: 9F2]

CAT#: AM26399PU-L

alpha 1 Antitrypsin (SERPINA1) mouse monoclonal antibody, clone 9F2, Aff - Purified

Product Images

Detect a-antitrypsin (a AAT) using antibody 9F2 at 1:5000 dilution

Specifications

Product Data

• Clone Name: 9F2
• Applications: ELISA, WB
• Recommended Dilution: Western blot: Detect α1-antitrypsin (AAT) using mAb 9F2 at 1:5000 dilution (0.2 μg/mL).
  ELISA.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human plasma derived α1-antitrypsin
• Specificity: This antibody with Human Alpha-1-antitrypsin.
• Formulation: 0.01M PBS pH7.2
  State: Aff - Purified
  State: Lyophilized Ig fraction
• Reconstitution Method: Double distillated water is recommended to adjust the final concentration to 1.00 mg/ml.
• Purification: Protein G affinity purified
• Conjugation: Unconjugated
• Storage: Store lyophilized at 2-8°C for 6 months or at -20°C long term.
  After reconstitution store the antibody undiluted at 2-8°C for one month
  or (in aliquots) at -20°C long term.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: serpin family A member 1
• Database Link:
  Entrez Gene 5265 Human
  UniProt ID P01009
• Background: Alpha-1-antitrypsin (AAT) is a protective protease inhibitor. It inhibits elastase released by neutrolphils during inflammatory reaction and irreversibly inactivates trypsin secreted in duodenum and elsewhere. α1-antitrypsin normally presents in plasma at 1.5-3.5 mg/mL, but increases in acute phase reaction, malignancies, pregnancy and trauma. Severe hereditary a1-antitrypsin deficiency can result in damages to alveoli, chronic obstructive pulmonary disease (COPD), and liver diseases such as jaundice and cirrhosis. The protein is also found in the neurofibrillary tangles and senile plaques in the brain lesions of Alzheimer’s disease, and has been suggested to contribute to the pathology of Alzheimer’s disease.
• Synonyms: SERPINA1, AAT