C3IP1 (KLHL12) Mouse Monoclonal Antibody [Clone ID: 2G2]
Other products for "KLHL12"
Specifications
Product Data | |
Clone Name | 2G2 |
Applications | ELISA, WB |
Recommended Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/10000. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Purified recombinant fragment of human KLHL12 expressed in E. Coli. |
Specificity | This antibody reacts to KLHL12. |
Formulation | State: Ascites State: Ascitic fluid containing 0.03% sodium azide. |
Conjugation | Unconjugated |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Predicted Protein Size | 63 kDa |
Gene Name | kelch like family member 12 |
Database Link | |
Background | Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.Tissue specificity: Highly expressed in testis and at lower levels in the submandibular salivary gland. |
Synonyms | KLHL12, C3IP1, CUL3-interacting protein 1 |
Reference Data |
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