PARP1 Mouse Monoclonal Antibody [Clone ID: 7A10]

CAT#: AM06413SU-N

PARP1 mouse monoclonal antibody, clone 7A10, Ascites

Product Images

Western blot analysis using PARP antibody Cat.-No AM06413SU-N against Jurkat (Lane 1), K562 (Lane 2), Hela (Lane 3), Raji (Lane 4), THP-1 (Lane 5) and SW620 (Lane 6) cell lysate.

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  Flow cytometric analysis of Jurkat cells using anti-PARP antibody Cat.-No AM06413SU-N (green) and negative control (purple).

Specifications

Product Data

• Clone Name: 7A10
• Applications: ELISA, FC, WB
• Recommended Dilution: ELISA: 1/10000.
  Western Blot: 1/500 - 1/2000.
  Flow Cytometry: 1/200 - 1/400.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Synthetic peptide of human PARP, conjugated to KLH.
• Formulation: State: Ascites
  State: Ascitic fluid containing 0.03% Sodium Azide.
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 117 kDa
• Gene Name: poly(ADP-ribose) polymerase 1
• Database Link:
  Entrez Gene 142 Human
  UniProt ID P09874
• Background: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
• Synonyms: PARP-1, ADPRT, ADPRT 1, PPOL