AXL Mouse Monoclonal Antibody [Clone ID: 7E10]

CAT#: AM06326SU-N

AXL mouse monoclonal antibody, clone 7E10, Ascites

Product Images

Western blot analysis using AXL antibody Cat.-No AM06326SU-N against extracellular domain of Human AXL (aa19-444).

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  Confocal Immunofluorescence analysis of methanol-fixed HEK293 cells trasfected with AXL-hIgGFc using AXL antibody Cat.-No AM06326SU-N (green), showing cytoplasmic and membrane localization. Blue: DRAQ5 fluorescent DNA dye.

Specifications

Product Data

• Clone Name: 7E10
• Applications: ELISA, IF, WB
• Recommended Dilution: ELISA: 1/10000.
  Western Blot: 1/500-1/2000.
  Immunofluorescence: 1/200-1/1000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified recombinant extracellular fragment of Human AXL fused with hIgGFc tag expressed in HEK293 cell line.
• Specificity: Recognizes AXL receptor tyrosine kinase
• Formulation: State: Ascites
  State: Ascitic fluid containing 0.03% Sodium Azide.
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 97.4 kDa
• Gene Name: AXL receptor tyrosine kinase
• Database Link:
  Entrez Gene 558 Human
  UniProt ID P30530
• Background: AXL receptor tyrosine kinase, also known as UFO, JTK11 is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.
• Synonyms: JTK11; UFO