AXL Mouse Monoclonal Antibody [Clone ID: 1B3A2]
Other products for "AXL"
Specifications
Product Data | |
Clone Name | 1B3A2 |
Applications | WB |
Recommended Dilution | ELISA: 1/10000. Western Bloting: 1/500 - 1/2000. |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Purified recombinant fragment of AXL (aa466-530) expressed in E. Coli. |
Specificity | Recognizes AXL receptor tyrosine kinase (AXL). |
Formulation | State: Ascites State: Ascitic fluid containing 0.03% Sodium Azide. |
Conjugation | Unconjugated |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Gene Name | AXL receptor tyrosine kinase |
Database Link | |
Background | The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified. |
Synonyms | JTK11; UFO |
Reference Data |
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