Creatine kinase M type (CKM) Mouse Monoclonal Antibody [Clone ID: 027-17186]

CAT#: AM00688PU-N

Creatine kinase M type (CKM) mouse monoclonal antibody, clone 027-17186, Purified

Specifications

Product Data

• Clone Name: 027-17186
• Applications: ELISA
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Purified human CK-MM
• Specificity: This antibody reacts to Creatine Kinase MM.
  Cross-reactivity:
  CK-MB: 50%
  CK-BB: <1%
• Formulation: 10mM Phosphate, pH 7.4 containing 150mM Sodium chloride and 0.09% Sodium azide
  State: Purified
  State: Liquid purified IgG (0.2µm filtered)
• Concentration: lot specific
• Purification: >90% pure (SDS-PAGE). Protein A chromatography
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one week or (in aliquots) at -40°C for longer.
  If aliquoted for long term storage, fill volume should be equal to or greater than 50% of the nominal fill volume of the vial used.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: creatine kinase, M-type
• Database Link:
  Entrez Gene 1158 Human
  UniProt ID P06732
• Background: Creatine Kinase MM (CK-MM) is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family.
• Synonyms: Creatine kinase M-type, Creatine kinase M chain, M-CK, CKM, Creatine kinase MM
• Note: Centrifuge before opening to ensure complete recovery of vial contents.

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Arginine and proline metabolism, Metabolic pathways