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shRNA Citations

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LAMP1 Large Putative PEST-like Sequence Motif at the Carboxyl Tail of Human Calcium Receptor Directs Lysosomal Degradation and Regulates Cell Surface Receptor Level, Xiaolei Zhuang, John K. Northup, and Kausik Ray, J. Biol. Chem., Feb 2012; 287: 4165 - 4176. TR311795

LAMP1 Visualizing Microtubule-Dependent Vasopressin Type 2 Receptor Trafficking Using a New High-Affinity Fluorescent Vasopressin Ligand, Sylvia Chen, Matthew J. Webber, Jean-Pierre Vilardaga, Ashok Khatri, Dennis Brown, Dennis A. Ausiello, Herbert Y. Lin, and Richard Bouley, Endocrinology, Oct 2011; 152: 3893 - 3904. TR311795

LAMP2 Chronic acidosis in the tumour microenvironment selects for overexpression of LAMP2 in the plasma membrane, Damaghi, M;Tafreshi, NK;Lloyd, MC;Sprung, R;Estrella, V;Wojtkowiak, JW;Morse, DL;Koomen, JM;Bui, MM;Gatenby, RA;Gillies, RJ;, Nat Commun Dec 2015 TR311794

LARP1 The RNA-binding protein LARP1 is a post-transcriptional regulator of survival and tumorigenesis in ovarian cancer, Hopkins, TG;Mura, M;Al-Ashtal, HA;Lahr, RM;Abd-Latip, N;Sweeney, K;Lu, H;Weir, J;El-Bahrawy, M;Steel, JH;Ghaem-Maghami, S;Aboagye, EO;Berman, AJ;Blagden, SP;, Nucleic Acids Res. Dec 2015 TF303581

LCN2 Mutant p53 Together with TGFß Signaling Influence Organ-Specific Hematogenous Colonization Patterns of Pancreatic Cancer, Zhong, Y;Macgregor-Das, AM;Saunders, T;Whittle, M;Makohon-Moore, A;Kohutek, Z;Poling, J;Herbst, B;Javier, B;Cope, L;Leach, SD;Hingorani, SR;Iacobuzio-Donahue, CA;, Clin. Cancer Res. 2016 TR511895

LCN2 Mutant p53 Together with TGFß Signaling Influence Organ-Specific Hematogenous Colonization Patterns of Pancreatic Cancer, Zhong, Y;Macgregor-Das, AM;Saunders, T;Whittle, M;Makohon-Moore, A;Kohutek, Z;Poling, J;Herbst, B;Javier, B;Cope, L;Leach, SD;Hingorani, SR;Iacobuzio-Donahue, CA;, Clin. Cancer Res. 2016 MR226233

LCN2 Lipocalin 2 Enhances Migration and Resistance against Cisplatin in Endometrial Carcinoma Cells, Miyamoto, T;Kashima, H;Yamada, Y;Kobara, H;Asaka, R;Ando, H;Higuchi, S;Ida, K;Mvunta, DH;Shiozawa, T;, PLoS ONE May 2016 TG311777

LCN2 Lipocalin 2 attenuates iron-related oxidative stress and prolongs the survival of ovarian clear cell carcinoma cells by up-regulating the CD44 variant, Yamada, Y;Miyamoto, T;Kashima, H;Kobara, H;, Free radical Research Feb 2016 TG311777

LDHA Sirtuin 6 suppresses hypoxia-induced inflammatory response in human osteoblasts via inhibition of reactive oxygen species production and glycolysis-A therapeutic implication in inflammatory bone resorption, Hou, KL;Lin, SK;Chao, LH;Hsiang-Hua Lai, E;Chang, CC;Shun, CT;Lu, WY;Wang, JH;Hsiao, M;Hong, CY;Kok, SH;, Biofactors 2016 TL311769

LEF1 MicroRNAs Regulate Pituitary Development, and MicroRNA 26b Specifically Targets Lymphoid Enhancer Factor 1 (Lef-1), Which Modulates Pituitary Transcription Factor 1 (Pit-1) Expression, Zichao Zhang, Sergio Florez, Arthur Gutierrez-Hartmann, James F. Martin, and Brad A. Amendt, J. Biol. Chem., Nov 2010; 285: 34718 - 34728 TR712526

LEO1 A role for the RNA pol II–associated PAF complex in AID-induced immune diversification, Katharina L. Willmann, Sara Milosevic, Siim Pauklin, Kerstin-Maike Schmitz, Gopinath Rangam, Maria T. Simon, Sarah Maslen, Mark Skehel, Isabelle Robert, Vincent Heyer, Ebe Schiavo, Bernardo Reina-San-Martin, and Svend K. Petersen-Mahrt, J. Exp. Med., Oct 2012; 209: 2099 - 2111. TG303551

LEO1 A role for the RNA pol II–associated PAF complex in AID-induced immune diversification, Katharina L. Willmann, Sara Milosevic, Siim Pauklin, Kerstin-Maike Schmitz, Gopinath Rangam, Maria T. Simon, Sarah Maslen, Mark Skehel, Isabelle Robert, Vincent Heyer, Ebe Schiavo, Bernardo Reina-San-Martin, and Svend K. Petersen-Mahrt, J. Exp. Med., Sep 2012; 10.1084/jem.20112145. TR303551

LGALS1 Galectin-1 suppression delineates a new strategy to inhibit myeloma-induced angiogenesis and tumoral growth in vivo., Storti, P;Marchica, V;Airoldi, I;Donofrio, G;Fiorini, E;Ferri, V;Guasco, D;Todoerti, K;Silbermann, R;Anderson, JL;Zhao, W;Agnelli, L;Bolzoni, M;Martella, E;Mancini, C;Campanini, N;Noonan, DM;Petronini, PG;Neri, A;Aversa, F;Roodman, GD;Giuliani, N;, Leukemia 2016 TL311756

LIMK1 Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects, Eva M Jimenez-Mateos, Tobias Engel, Paula Merino-Serrais, Ross C McKiernan, Katsuhiro Tanaka, Genshin Mouri, Takanori Sano, Colm O'Tuathaigh, John L Waddington, Suzanne Prenter, Norman Delanty, Michael A Farrell, Donncha F O'Brien, Ronán M Conroy, Raymond L Stallings, Javier DeFelipe & David C Henshall, Nature Medicine 18, 1087-1094 doi:10.1038/nm.2834 TR320403

LMNA Promoter hypermethylation as a mechanism for Lamin A/C silencing in a subset of neuroblastoma cells, Rauschert, I;Aldunate, F;Preussner, J;Arocena-Sutz, M;Peraza, V;Looso, M;Benech, JC;Agrelo, R;, PLoS ONE 2017 TG303510

LNP1 Lunapark Is a Component of a Ubiquitin Ligase Complex Localized to the Endoplasmic Reticulum Three-way Junctions, Zhao, Y;Zhang, T;Huo, H;Ye, Y;Liu, Y;, J. Biol. Chem. 2016 TR320968

LOXL2 Lysyl oxidase-like protein-2 regulates sprouting angiogenesis and type IV collagen assembly in the endothelial basement membrane, Marine Bignon, Cathy Pichol-Thievend, Julie Hardouin, Marilyne Malbouyres, Nicolas Bréchot, Luiz Nasciutti, Alain Barret, Jérémie Teillon, Emilie Guillon, Eric Etienne, Michel Caron, Raymonde Joubert-Caron, Catherine Monnot, Florence Ruggiero, Laurent Muller, and Stéphane Germain, Blood, Oct 2011; 118: 3979 - 3989. TR311699

LPAR1 Lysophosphatidic acid signaling via LPA1 and LPA3 regulates cellular functions during tumor progression in pancreatic cancer cells, Fukushima, K;Takahashi, K;Yamasaki, E;Onishi, Y;Fukushima, N;Honoki, K;Tsujiuchi, T;, Experimental Cell Research 2017 TR313300

LPAR1 Different induction of LPA receptors by chemical liver carcinogens regulates cellular functions of liver epithelial WB-F344 cells, Hirane, M;Ishii, S;Tomimatsu, A;Fukushima, K;Takahashi, K;Fukushima, N;Honoki, K;Tsujiuchi, T;, Mol. Carcinog. Sep 2015 TF712271

LPAR1 LPA signaling through LPA receptors regulates cellular functions of endothelial cells treated with anticancer drugs, Mori, S;Araki, M;Ishii, S;Hirane, M;Fukushima, K;Tomimatsu, A;Takahashi, K;Fukushima, N;Tsujiuchi, T;, Mol. Cell. Biochem. Jun 2015 TG509224

 

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