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Muscarinic Receptor Activation Increases hERG Channel Expression through Phosphorylation of Ubiquitin Ligase Nedd4-2, Wang, T;Hogan-Cann, A;Kang, Y;Cui, Z;Guo, J;Yang, T;Lamothe, SM;Li, W;Ma, A;Fisher, JT;Zhang, S;, Mol. Pharmacol. 877-86 85 6. March 2014 [CHRM3 SKU# RC212436]

NEDD9 crucially regulates TGF-ß-triggered epithelial-mesenchymal transition and cell invasion in prostate cancer cells: Involvement in cancer progressiveness, Morimoto, K;Tanaka, T;Nitta, Y;Ohnishi, K;Kawashima, H;Nakatani, T;, Prostate 901-10 74 8. April 2014 [NEDD9 SKU# RC207200]

Chimeric Proteins Combining Phosphatase and Cellulose-Binding Activities: Proof-of-Concept and Application in the Hydrolysis of Paraoxon, Goncalves, LM;Chaimovich, H;Cuccovia, IM;Marana, SR;, Protein Pept. Lett. May 2014 [PON1 SKU# SC119866]

De novo CCND2 mutations leading to stabilization of cyclin D2 cause megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome, Mirzaa, GM;Parry, DA;Fry, AE;Giamanco, KA;Schwartzentruber, J;Vanstone, M;Logan, CV;Roberts, N;Johnson, CA;Singh, S;Kholmanskikh, SS;Adams, C;Hodge, RD;Hevner, RF;Bonthron, DT;Braun, KP;Faivre, L;Rivière, JB;St-Onge, J;Gripp, KW;Mancini, GM;Pang, K;Sweeney, E;van Esch, H;Verbeek, N;Wieczorek, D;Steinraths, M;Majewski, J;FORGE Canada Consortium, ;Boycott, KM;Pilz, DT;Ross, ME;Dobyns, WB;Sheridan, EG;, Nat. Genet. 510-5 46 5. May 2014 [CCND2 SKU# RC210316]

Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis, Johnson, JO;Pioro, EP;Boehringer, A;Chia, R;Feit, H;Renton, AE;Pliner, HA;Abramzon, Y;Marangi, G;Winborn, BJ;Gibbs, JR;Nalls, MA;Morgan, S;Shoai, M;Hardy, J;Pittman, A;Orrell, RW;Malaspina, A;Sidle, KC;Fratta, P;Harms, MB;Baloh, RH;Pestronk, A;Weihl, CC;Rogaeva, E;Zinman, L;Drory, VE;Borghero, G;Mora, G;Calvo, A;Rothstein, JD;ITALSGEN, ;Drepper, C;Sendtner, M;Singleton, AB;Taylor, JP;Cookson, MR;Restagno, G;Sabatelli, M;Bowser, R;Chiò, A;Traynor, BJ;, Nat. Neurosci. 664-6 17 5. May 2014 [MATR3 SKU# TP323258]

POT1 loss-of-function variants predispose to familial melanoma, Robles-Espinoza, CD;Harland, M;Ramsay, AJ;Aoude, LG;Quesada, V;Ding, Z;Pooley, KA;Pritchard, AL;Tiffen, JC;Petljak, M;Palmer, JM;Symmons, J;Johansson, P;Stark, MS;Gartside, MG;Snowden, H;Montgomery, GW;Martin, NG;Liu, JZ;Choi, J;Makowski, M;Brown, KM;Dunning, AM;Keane, TM;López-Otín, C;Gruis, NA;Hayward, NK;Bishop, DT;Newton-Bishop, JA;Adams, DJ;, Nat. Genet. 478-81 46 5. May 2014 [POT1 SKU# SC112647]

The adaptor TRAF5 limits the differentiation of inflammatory CD4(+) T cells by antagonizing signaling via the receptor for IL-6, Nagashima, H;Okuyama, Y;Asao, A;Kawabe, T;Yamaki, S;Nakano, H;Croft, M;Ishii, N;So, T;, Nat. Immunol. 449-56 15 5. May 2014 [TRAF5 SKU# MR208836]

18ß-Glycyrrhetinic Acid Suppresses Cell Proliferation through Inhibiting Thromboxane Synthase in Non-Small Cell Lung Cancer, Huang, RY;Chu, YL;Huang, QC;Chen, XM;Jiang, ZB;Zhang, X;Zeng, X;, PLoS ONE e93690 9 4. April 2014 [TxAS SKU# SC109823]

A Bacteriophage Capsid Protein Provides a General Amyloid Interaction Motif (GAIM) That Binds and Remodels Misfolded Protein Assemblies, Krishnan, R;Tsubery, H;Proschitsky, MY;Asp, E;Lulu, M;Gilead, S;Gartner, M;Waltho, J;Davis, PJ;Hounslow, AM;Kirschner, DA;Inouye, H;Myszka, DG;Wright, J;Solomon, B;Fisher, RA;, J. Mol. Biol. April 2014 [SCNA SKU# SC119919]

A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect, Lopez-Serra, P;Marcilla, M;Villanueva, A;Ramos-Fernandez, A;Palau, A;Leal, L;Wahi, JE;Setien-Baranda, F;Szczesna, K;Moutinho, C;Martinez-Cardus, A;Heyn, H;Sandoval, J;Puertas, S;Vidal, A;Sanjuan, X;Martinez-Balibrea, E;Viñals, F;Perales, JC;Bramsem, JB;Ørntoft, TF;Andersen, CL;Tabernero, J;McDermott, U;Boxer, MB;Heiden, MG;Albar, JP;Esteller, M;, Nat Commun 3608 5 . April 2014 [SLC2A1 SKU# TL309344]

A High-Throughput Fluorimetric Assay for 2-hydroxyglutarate Identifies Zaprinast as a Glutaminase Inhibitor, Elhammali, A;Ippolito, JE;Collins, L;Crowley, J;Marasa, J;Piwnica-Worms, D;, Cancer Discov . April 2014 [IDH1 SKU# TA500610]

A nanotechnological, molecular-modeling, and immunological approach to study the interaction of the anti-tumorigenic peptide p28 with the p53 family of proteins, Coppari, E;Yamada, T;Bizzarri, AR;Beattie, CW;Cannistraro, S;, Int J Nanomedicine 1799-813 9 . April 2014 [p63 SKU# SC128232]

A New Polymorphism Biomarker rs629367 Associated with Increased Risk and Poor Survival of Gastric Cancer in Chinese by Up-Regulated miRNA-let-7a Expression, Xu, Q;Dong, Q;He, C;Liu, W;Sun, L;Liu, J;Xing, C;Li, X;Wang, B;Yuan, Y;, PLoS ONE e95249 9 4. April 2014 [MIR-let-7a SKU# SC400707]

A novel chimeric antigen receptor against PSCA mediates tumor destruction in a humanized mouse model of pancreatic cancer, Abate-Daga, D;Lagisetty, KH;Tran, E;Zheng, Z;Gattinoni, L;Yu, Z;Burns, WR;Miermont, AM;Teper, Y;Rudloff, U;Restifo, NP;Feldman, SA;Rosenberg, SA;Morgan, RA;, Hum. Gene Ther. April 2014 [pancreatic adenocarcinoma SKU# ]

A novel role for the Proteasomal Chaperone PSMD9 and hnRNPA1 in enhancing I?Ba degradation and NF-?B activation - Functional Relevance of predicted PDZ domain-motif interaction, Sahu, I;Sangith, N;Ramteke, M;Gadre, R;Venkatraman, P;, FEBS J. April 2014 [PSMD9 SKU# SC118384]


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