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siRNA Citations

CD163 and IgG Codefend against Cytotoxic Hemoglobin via Autocrine and Paracrine Mechanisms, Karthik Subramanian, Ruijuan Du, Nguan Soon Tan, Bow Ho, and Jeak Ling Ding, J. Immunol., May 2013; 190: 5267 - 5278. [FCGR2A ]

The Syndecan-4/Protein Kinase Ca Pathway Mediates Prostaglandin E2-induced Extracellular Regulated Kinase (ERK) Activation in Endothelial Cells and Angiogenesis in Vivo, Federico Corti, Federica Finetti, Marina Ziche, and Michael Simons, J. Biol. Chem., May 2013; 288: 12712 - 12721. [PRKCA ]

Acetylated hsp70 and KAP1-mediated Vps34 SUMOylation is required for autophagosome creation in autophagy, Yonghua Yang, Warren Fiskus, Bao Yong, Peter Atadja, Yoshinori Takahashi, Tej K. Pandita, Hong-Gang Wang, and Kapil N. Bhalla, PNAS, Apr 2013; 110: 6841 - 6846. [KAP1 ]

GX15-070 (Obatoclax) Induces Apoptosis and Inhibits Cathepsin D- and L–Mediated Autophagosomal Lysis in Antiestrogen-Resistant Breast Cancer Cells, Jessica L. Schwartz-Roberts, Ayesha N. Shajahan, Katherine L. Cook, Anni Wärri, Mones Abu-Asab, and Robert Clarke, Mol. Cancer Ther., Apr 2013; 12: 448 - 459. [BECN1 ]

SCO2 Induces p53-Mediated Apoptosis by Thr845 Phosphorylation of ASK-1 and Dissociation of the ASK-1–Trx Complex, Esha Madan, Rajan Gogna, Periannan Kuppusamy, Madan Bhatt, Abbas Ali Mahdi, and Uttam Pati, Mol. Cell. Biol., Apr 2013; 33: 1285 - 1302. [p53]

IL-27 inhibits HIV-1 infection in human macrophages by down-regulating host factor SPTBN1 during monocyte to macrophage differentiation, Lue Dai, Kristy B. Lidie, Qian Chen, Joseph W. Adelsberger, Xin Zheng, DaWei Huang, Jun Yang, Richard A. Lempicki, Tauseef Rehman, Robin L. Dewar, Yanmei Wang, Ronald L. Hornung, Kelsey A. Canizales, Stephen J. Lockett, H. Clifford Lane, and Tomozumi Imamichi, J. Exp. Med., Mar 2013; 210: 517 - 534. [SPTBN1 ]

Protein Kinases D2 and D3 Are Novel Growth Regulators in HCC1806 Triple-negative Breast Cancer Cells, QIN HAO, RAYMOND MCKENZIE, HUACHEN GAN, and HUA TANG, Anticancer Res, Feb 2013; 33: 393 - 399. [PRKCA]

Targeting the Metastasis Suppressor, NDRG1, Using Novel Iron Chelators: Regulation of Stress Fiber-Mediated Tumor Cell Migration via Modulation of the ROCK1/pMLC2 Signaling Pathway, Jing Sun, Daohai Zhang, Ying Zheng, Qian Zhao, Minhua Zheng, Zaklina Kovacevic, and Des R. Richardson, Mol. Pharmacol., Feb 2013; 83: 454 - 469. [ROCK1 ]

Taxifolin Enhances Andrographolide-Induced Mitotic Arrest and Apoptosis in Human Prostate Cancer Cells via Spindle Assembly Checkpoint Activation , Zhang ZR, Al Zaharna M, Wong MM, Chiu SK, Cheung HY., PLoS One. 2013;8(1):e54577 [MAD2L1 ]

cAMP-responsive Element Modulator a (CREMa) Contributes to Decreased Notch-1 Expression in T Cells from Patients with Active Systemic Lupus Erythematosus (SLE), Thomas Rauen, Alexandros P. Grammatikos, Christian M. Hedrich, Jürgen Floege, Klaus Tenbrock, Kim Ohl, Vasileios C. Kyttaris, and George C. Tsokos, J. Biol. Chem., Dec 2012; 287: 42525 - 42532. [NOTCH1]

miR-23b Represses Proto-oncogene Src Kinase and Functions as Methylation-Silenced Tumor Suppressor with Diagnostic and Prognostic Significance in Prostate Cancer, Shahana Majid, Altaf A. Dar, Sharanjot Saini, Sumit Arora, Varahram Shahryari, Mohd Saif Zaman, Inik Chang, Soichiro Yamamura, Yuichiro Tanaka, Guoren Deng, and Rajvir Dahiya, Cancer Res., Dec 2012; 72: 6435 - 6446. [SRC ]

The p53 target gene desmocollin 3 acts as a novel tumor suppressor through inhibiting EGFR/ERK pathway in human lung cancer, Tiantian Cui, Yuan Chen, Linlin Yang, Thomas Knösel, Otmar Huber, Manuela Pacyna-Gengelbach, and Iver Petersen, Carcinogenesis, Dec 2012; 33: 2326 - 2333. [DSC3]

A possible gene silencing mechanism: Hypermethylation of the Keap1 promoter abrogates binding of the transcription factor Sp1 in lung cancer cells , D Guo, B Wu, J Yan, X Li, H Sun, D Zhou, Biochem Biophys Res Commun. 2012 Nov 9;428(1):80-5 [SP1]