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siRNA Citations

IL-27 inhibits HIV-1 infection in human macrophages by down-regulating host factor SPTBN1 during monocyte to macrophage differentiation, Lue Dai, Kristy B. Lidie, Qian Chen, Joseph W. Adelsberger, Xin Zheng, DaWei Huang, Jun Yang, Richard A. Lempicki, Tauseef Rehman, Robin L. Dewar, Yanmei Wang, Ronald L. Hornung, Kelsey A. Canizales, Stephen J. Lockett, H. Clifford Lane, and Tomozumi Imamichi, J. Exp. Med., Mar 2013; 210: 517 - 534. [SPTBN1 ]

Protein Kinases D2 and D3 Are Novel Growth Regulators in HCC1806 Triple-negative Breast Cancer Cells, QIN HAO, RAYMOND MCKENZIE, HUACHEN GAN, and HUA TANG, Anticancer Res, Feb 2013; 33: 393 - 399. [PRKCA]

Targeting the Metastasis Suppressor, NDRG1, Using Novel Iron Chelators: Regulation of Stress Fiber-Mediated Tumor Cell Migration via Modulation of the ROCK1/pMLC2 Signaling Pathway, Jing Sun, Daohai Zhang, Ying Zheng, Qian Zhao, Minhua Zheng, Zaklina Kovacevic, and Des R. Richardson, Mol. Pharmacol., Feb 2013; 83: 454 - 469. [ROCK1 ]

Taxifolin Enhances Andrographolide-Induced Mitotic Arrest and Apoptosis in Human Prostate Cancer Cells via Spindle Assembly Checkpoint Activation , Zhang ZR, Al Zaharna M, Wong MM, Chiu SK, Cheung HY., PLoS One. 2013;8(1):e54577 [MAD2L1 ]

cAMP-responsive Element Modulator a (CREMa) Contributes to Decreased Notch-1 Expression in T Cells from Patients with Active Systemic Lupus Erythematosus (SLE), Thomas Rauen, Alexandros P. Grammatikos, Christian M. Hedrich, Jürgen Floege, Klaus Tenbrock, Kim Ohl, Vasileios C. Kyttaris, and George C. Tsokos, J. Biol. Chem., Dec 2012; 287: 42525 - 42532. [NOTCH1]

miR-23b Represses Proto-oncogene Src Kinase and Functions as Methylation-Silenced Tumor Suppressor with Diagnostic and Prognostic Significance in Prostate Cancer, Shahana Majid, Altaf A. Dar, Sharanjot Saini, Sumit Arora, Varahram Shahryari, Mohd Saif Zaman, Inik Chang, Soichiro Yamamura, Yuichiro Tanaka, Guoren Deng, and Rajvir Dahiya, Cancer Res., Dec 2012; 72: 6435 - 6446. [SRC ]

The p53 target gene desmocollin 3 acts as a novel tumor suppressor through inhibiting EGFR/ERK pathway in human lung cancer, Tiantian Cui, Yuan Chen, Linlin Yang, Thomas Knösel, Otmar Huber, Manuela Pacyna-Gengelbach, and Iver Petersen, Carcinogenesis, Dec 2012; 33: 2326 - 2333. [DSC3]

A possible gene silencing mechanism: Hypermethylation of the Keap1 promoter abrogates binding of the transcription factor Sp1 in lung cancer cells , D Guo, B Wu, J Yan, X Li, H Sun, D Zhou, Biochem Biophys Res Commun. 2012 Nov 9;428(1):80-5 [SP1]

cAMP response element modulator a controls IL2 and IL17A expression during CD4 lineage commitment and subset distribution in lupus, Christian M. Hedrich, Jose C. Crispin, Thomas Rauen, Christina Ioannidis, Sokratis A. Apostolidis, Mindy S. Lo, Vasileios C. Kyttaris, and George C. Tsokos, PNAS, Oct 2012; 109: 16606 - 16611. [DNMT3a]

Desmoplakin acts as a tumor suppressor by inhibition of the Wnt/ß-catenin signaling pathway in human lung cancer, Linlin Yang, Yuan Chen, Tiantian Cui, Thomas Knösel, Qing Zhang, Kai Frederik Albring, Otmar Huber, and Iver Petersen, Carcinogenesis, Oct 2012; 33: 1863 - 1870. [DSP]

Ectopic ATP Synthase Blockade Suppresses Lung Adenocarcinoma Growth by Activating the Unfolded Protein Response , Hsin-Yi Chang, Hsuan-Cheng Huang, Tsui-Chin Huang, Pan-Chyr Yang, Yi-Ching Wang, and Hsueh-Fen Juan, Cancer Res., Sep 2012; 72: 4696 - 4706. [EIF2AK3 ]

CBX4-mediated SUMO modification regulates BMI1 recruitment at sites of DNA damage , Ismail Hassan Ismail, Jean-Philippe Gagné, Marie-Christine Caron, Darin McDonald, Zhizhong Xu, Jean-Yves Masson, Guy G. Poirier, and Michael J. Hendzel, Nucleic Acids Res., Jul 2012; 40: 5497 - 5510. [CBX4 ]

PTX3 Controls Activation of Matrix Metalloproteinase 1 and Apoptosis in Conjunctivochalasis Fibroblasts , Ping Guo, Su-Zhen Zhang, Hua He, Ying-Ting Zhu, and Scheffer C. G. Tseng, Invest. Ophthalmol. Vis. Sci., Jun 2012; 53: 3414 - 3423. [PTX3 ]

Identification of CTCF as a master regulator of the clustered protocadherin genes , Michal Golan-Mashiach, Moshe Grunspan, Rafi Emmanuel, Liron Gibbs-Bar, Rivka Dikstein, and Ehud Shapiro, Nucleic Acids Res., Apr 2012; 40: 3378 - 3391. [CTCF ]

cAMP-responsive Element Modulator a (CREMa) Suppresses IL-17F Protein Expression in T Lymphocytes from Patients with Systemic Lupus Erythematosus (SLE) , Christian M. Hedrich, Thomas Rauen, Katalin Kis-Toth, Vasileios C. Kyttaris, and George C. Tsokos, J. Biol. Chem., Feb 2012; 287: 4715 - 4725. [Cy-3-labeled control siRNA]