Mitogen-Activated Protein Kinase-Dependent Interleukin-1a Intracrine Signaling Is Modulated by YopP during Yersinia enterocolitica Infection
Infect. Immun., Jan 2012; 80: 289 - 297.
[IL1A]
ETS1 transcriptional activity is increased in advanced prostate cancer and promotes the castrate-resistant phenotype
Carcinogenesis, Jan 2012; 10.1093/carcin/bgs007.
[ETS1
]
PNAS Plus: TANK-binding kinase 1 (TBK1) controls cell survival through PAI-2/serpinB2 and transglutaminase 2
PNAS, Jan 2012; 109: E177 - E186.
[SERPINB2
]
Heparanase and Syndecan-1 Interplay Orchestrates Fibroblast Growth Factor-2-induced Epithelial-Mesenchymal Transition in Renal Tubular Cells
J. Biol. Chem., Jan 2012; 287: 1478 - 1488.
[HPSE
]
Exact-shRNA: Custom shRNA service
Exact-shRNA is an shRNA service for the special needs outside our pre-designed shRNA products. Examples are
shRNA targeting species other than Human, Mouse or Rat
Integrate an effective siRNA oligo sequence into an shRNA vector
Isoform-specific knock down
Have shRNA constructs that target multiple species
Reproduce a published result where shRNA sequence is available/disclosed
There are two modes of service with Exact-shRNA:
Self-design: Customers specify the short hairpin sequences (stem and loop), choose a vector and OriGene constructs the plasmid. This is targeted to researchers who have gained knowledge of the effective target sequence, either from previous research or from published work. Up to 4 constructs are allowed for each project. Additional constructs can be submitted as a new project.
OriGene-design: Customers define the transcript sequence(s) and OriGene designs the shRNA (stem and loop) using our proprietary algorithm. Four constructs will be designed whenever possible.
Click on a service above to fill out the request form. When placing an order, just refer to the catalog number on the request form.
If you would like some assistance in the design of your shRNA constructs, we have experienced molecular biologists in our technical support team ready to help. Contact the Exact-shRNA team at 301.340.3188 option 2.
