OriGene shRNA Recent Citations
Adenosine Signaling Mediates SUMO-1 Modification of IB during Hypoxia and Reoxygenation ,J. Biol. Chem., May 2009; 284: 13686 - 13695. [SUMO1]
Copper transport into the secretory pathway is regulated by oxygen in macrophages , J. Cell Sci., May 2009; 122: 1315 - 1321. [ATP7A]
HMGB1 Is Phosphorylated by Classical Protein Kinase C and Is Secreted by a Calcium-Dependent Mechanism , J. Immunol., May 2009; 182: 5800 - 5809. [PDK1]
Loss of PINK1 Function Promotes Mitophagy through Effects on Oxidative Stress and Mitochondrial Fission , J. Biol. Chem., May 2009; 284: 13843 - 13855. [PINK1]
NHERF1 Regulates Parathyroid Hormone Receptor Desensitization: Interference with ß-Arrestin Binding , Mol. Pharmacol., May 2009; 75: 1189 - 1197. [NHERF1]
NORE1A Tumor Suppressor Candidate Modulates p21CIP1 via p53 , Cancer Res., May 2009; 10.1158/0008-5472.CAN-08-3672. [RASSF5]
Proepithelin is an autocrine growth factor for bladder cancer , Francesca Lovat, Carcinogenesis, May 2009; 30: 861 - 868. [GRN(PEPI)]
Specific function of phosphoinositide 3-kinase beta in the control of DNA replication , PNAS, May 2009; 106: 7525 - 7530. [PIK3CB]
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HuSH-29: Genome-wide shRNA
Now available for rat genes
HuSH-29 are pre-designed shRNA with genome wide coverage (human, mouse and rat) that delivers guaranteed knockdown. The same superior design is also offered for other species through Exact-shRNA . A new offering of pGFP-V-RS and pRFP-C-RS vectors enable easy monitoring of transfection efficiency. Learn more about HuSH-29... )
Features and Benefits
Pre-designed 29mer targets against Human, Mouse & Rat
Three retroviral vector options:
pRS: basic retroviral vector without fluorescence
pGFP-V-RS: pRS with GFP to monitor transfection
pRFP-C-RS: pRS with RFP as second fluorescence, ideal for double knock down with pGFP-V-RS
5ug of purified plasmid for immediate transfection
Guaranteed successful gene knockdown (=70%)
Versatile applications: transient or stable transfection or retroviral infection
As low as $595 for a kit (4 gene-specific shRNA and two negative controls)
Our scientists will answer your technical questions from 9AM to 7PM ET. Call 1-888-267-4436
Applications:
Gene silencing through transient or stable transfection
Gene silencing through retroviral transduction
Ideal for shRNA validation by co-transfection of RFP-shRNA with GFP-ORF clones
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