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OriGene in recent publications
Repurposing of Proton Pump Inhibitors as first identified small molecule inhibitors of endo-β-N-acetylglucosaminidase (ENGase) for the treatment of NGLY1 deficiency, a rare genetic disease Bioorg. Med. Chem. Lett. 2017 [ENGASE]

The lipid moiety 7-ketocholesteryl-9-carboxynonanoate mediates binding interaction of oxLDL to LOX-1 and upregulates ABCA1 expression through PPARγ Life Sci. 2017 [OLR1]

Human GRP78 affinity towards its signaling partners Ire1α and PERK is differently modulated by an unfolded protein client Biochem. Biophys. Res. Commun. 2017 [HSPA5]

Human GRP78 affinity towards its signaling partners Ire1α and PERK is differently modulated by an unfolded protein client Biochem. Biophys. Res. Commun. 2017 [ERN1]

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24 TrueORF belong to pathway "valine, leucine and isoleucine biosynthesis"

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SKUAccnSymbolDescriptionShipping
RC200625NM_001190BCAT2BCAT2 (Myc-DDK-tagged)-Human branched chain amino-acid transaminase 2, mitochondrial (BCAT2), nuclear gene encoding mitochondrial protein, transcript variant aImmediate
RC201089NM_006295VARSVARS (Myc-DDK-tagged)-Human valyl-tRNA synthetase (VARS), nuclear gene encoding mitochondrial proteinImmediate
RC201230NM_000925PDHBPDHB (Myc-DDK-tagged)-Human pyruvate dehydrogenase (lipoamide) beta (PDHB), nuclear gene encoding mitochondrial protein, transcript variant 13 week
RC201831NM_000284PDHA1PDHA1 (Myc-DDK-tagged)-Human pyruvate dehydrogenase (lipoamide) alpha 1 (PDHA1), nuclear gene encoding mitochondrial protein, transcript variant 1Immediate
RC205207NM_015340LARS2LARS2 (Myc-DDK-tagged)-Human leucyl-tRNA synthetase 2, mitochondrial (LARS2), nuclear gene encoding mitochondrial proteinImmediate
RC205416NM_005390PDHA2PDHA2 (Myc-DDK-tagged)-Human pyruvate dehydrogenase (lipoamide) alpha 2 (PDHA2)Immediate
RC211310NM_020442VARS2VARS2 (Myc-DDK-tagged)-Human valyl-tRNA synthetase 2, mitochondrial (putative) (VARS2), nuclear gene encoding mitochondrial protein, transcript variant 2Immediate
RC211919NM_018060IARS2IARS2 (Myc-DDK-tagged)-Human isoleucyl-tRNA synthetase 2, mitochondrial (IARS2), nuclear gene encoding mitochondrial proteinImmediate
RC212911NM_002161IARSIARS (Myc-DDK-tagged)-Human isoleucyl-tRNA synthetase (IARS), transcript variant shortImmediate
RC213208NM_013417IARSIARS (Myc-DDK-tagged)-Human isoleucyl-tRNA synthetase (IARS), transcript variant longImmediate
RC219229NM_005504BCAT1BCAT1 (Myc-DDK-tagged)-Human branched chain amino-acid transaminase 1, cytosolic (BCAT1), transcript variant 1Immediate
RC221682NM_020117LARSLARS (Myc-DDK-tagged)-Human leucyl-tRNA synthetase (LARS)Immediate
RC228234NM_001164773BCAT2BCAT2 (Myc-DDK-tagged)-Human branched chain amino-acid transaminase 2, mitochondrial (BCAT2), transcript variant bImmediate
RC229891NM_001178092BCAT1BCAT1 (Myc-DDK-tagged)-Human branched chain amino-acid transaminase 1, cytosolic (BCAT1), transcript variant 3Immediate
RC229907NM_001173468PDHBPDHB (Myc-DDK-tagged)-Human pyruvate dehydrogenase (lipoamide) beta (PDHB), nuclear gene encoding mitochondrial protein, transcript variant 2Immediate
RC229924NM_001178091BCAT1BCAT1 (Myc-DDK-tagged)-Human branched chain amino-acid transaminase 1, cytosolic (BCAT1), transcript variant 2Immediate
RC229934NM_001173456PDHA1PDHA1 (Myc-DDK-tagged)-Human pyruvate dehydrogenase (lipoamide) alpha 1 (PDHA1), nuclear gene encoding mitochondrial protein, transcript variant 4Immediate
RC229972NM_001178094BCAT1BCAT1 (Myc-DDK-tagged)-Human branched chain amino-acid transaminase 1, cytosolic (BCAT1), transcript variant 5Immediate
RC229995NM_001173455PDHA1PDHA1 (Myc-DDK-tagged)-Human pyruvate dehydrogenase (lipoamide) alpha 1 (PDHA1), nuclear gene encoding mitochondrial protein, transcript variant 3Immediate
RC229999NM_001178093BCAT1BCAT1 (Myc-DDK-tagged)-Human branched chain amino-acid transaminase 1, cytosolic (BCAT1), transcript variant 4Immediate

 

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