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Home Recombinant Human Proteins All DES Proteins

DES (NM_001927) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP720562 Recombinant protein of human desmin (DES), 10 ug (Larger pack size?) $299 5 Days
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OriGene Data
Species:Human Expression Host:E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC205685, encoding the polypeptide (Val260-Leu470) of human DES
Tag:C-terminal HIS Predicted MW:26.7 kDa
Purity:>95% as determined by SDS-PAGE and Coomassie blue staining
Concentration:Resuspend the protein to the desired concentration in proper buffer.
Buffer:Lyophilized from a 0.2 µM filtered solution of 20mM Phosphate buffer, 150mM NaCl, pH 7.2. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Endotoxin: < 0.1 EU per µg protein as determined by LAL test
Protein Families: Druggable Genome
Protein Pathways: Hypertrophic cardiomyopathy (HCM)Arrhythmogenic right ventricular cardiomyopathy (ARVC)Dilated cardiomyopathy
Protein Data
Protein Image

Reference Data
RefSeq: NP_001918 RefSeq Size: 2268 RefSeq ORF: 1413
LocusID: 1674 Cytogenetic: 2q35  
Synonyms : CSM1; CSM2; LGMD2R
Summary: This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq, Jul 2008].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich


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