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Home Recombinant Human Proteins All GADD45B Proteins

GADD45B (NM_015675) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP720537 Recombinant protein of human growth arrest and DNA-damage-inducible, beta (GADD45B), 10 µg (Larger pack size?) 299 5 Days
TA310513 Rabbit Monoclonal antibody against GADD45 beta (GADD45B) $325 In Stock
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Also for GADD45B (NM_015675)
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OriGene Data
Species:Human Expression Host:E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC213354, encoding the full length polypeptide (Met1-Arg160) of human GADD45B
Tag:C-terminal HIS Predicted MW:20.0 kDa
Purity:>95% as determined by SDS-PAGE and Coomassie blue staining
Concentration:Resuspend the protein to the desired concentration in proper buffer.
Buffer:Lyophilized from a 0.2 µM filtered solution of 20mM Phosphate buffer, 150mM NaCl, pH 7.4. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Endotoxin: < 0.1 EU per µg protein as determined by LAL test
Protein Families: Druggable Genome
Protein Pathways: MAPK signaling pathwayCell cyclep53 signaling pathway
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_056490 RefSeq Size: 1121 RefSeq ORF: 486
LocusID: 4616 Cytogenetic: 19p13.3  
Synonyms : GADD45BETA; MYD118
Summary: This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth. [provided by RefSeq, Jul
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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