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Home Recombinant Human Proteins All BTK Proteins

BTK (NM_000061) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP710016 Recombinant protein of human Bruton agammaglobulinemia tyrosine kinase (BTK),full length, with C-terminal polyhistidine tag, expressed in sf9 cell, 20 ug (Larger pack size?) $399 In Stock
TA501119 anti-BTK mouse monoclonal antibody, clone OTI15G8 (formerly 15G8) $379 In Stock
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OriGene Data
Species:Human Expression Host:Sf9 cells
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC211582, encoding human full-length BTK
Tag:C-terminal HIS Predicted MW:76 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:50mM Tris-HCl pH8.0, 150mM NaCl, 20% glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
Protein Families: Protein KinaseDruggable Genome
Protein Pathways: B cell receptor signaling pathwayFc epsilon RI signaling pathwayPrimary immunodeficiency
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_000052 RefSeq Size: 2591 RefSeq ORF: 1977
LocusID: 695 Cytogenetic: Xq22.1  
Synonyms : AGMX1; AT; ATK; BPK; IMD1; PSCTK1; XLA
Summary: The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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