ADH7 (NM_000673) Purified Human Protein

Species: Human Expression Host: Human 293HEK cells Expression cDNA Clone and Sequence Recombinant protein was produced with TrueORF clone, RC224304. Click on the TrueORF clone link to view cDNA and protein sequences. Tag: C-terminal MYC/DDK Predicted MW: 41.3 kDa Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining Mass Spec Validation: This protein has been positively validated by MS/MS by Dr. Robert Moritz at The Institute of Systems Biology. Concentration: >50 ug/mL as determined by microplate BCA method Buffer and Storage: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. Protein Families: Druggable Genome Protein Pathways: Glycolysis / GluconeogenesisFatty acid metabolismTyrosine metabolismRetinol metabolismMetabolism of xenobiotics by cytochrome P450Drug metabolism - cytochrome P450More Pathways >>

Protein Data

RefSeq: NP_000664	RefSeq Size: 2147	RefSeq ORF: 1161
LocusID: 131	Cytogenetic: 4q23
Synonyms : ADH4
Summary: This gene encodes class IV alcohol dehydrogenase 7 mu or sigma subunit, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The enzyme encoded by this gene is inefficient in ethanol oxidation, but is the most active as a retinol dehydrogenase; thus it may participate in the synthesis of retinoic acid, a hormone important for cellular differentiation. The expression of this gene is much more abundant in stomach than liver, thus differing from the other known gene family members. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].

Researchers who bought this clone have also purchased:

Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide (ADH7), transcript variant 2 as transfection-ready DNA • GFP-tagged ORF clone of Homo sapiens alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide (ADH7), transcript variant 2 as transfection-ready DNA • Lenti ORF clone of Human alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide (ADH7), transcript variant 2, mGFP tagged • Lenti ORF clone of Human alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide (ADH7), transcript variant 2 , Myc-DDK-tagged • Myc-DDK-tagged ORF clone of Homo sapiens alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide (ADH7), transcript variant 2 as 200 ug transfection-ready DNA Related Lysate from OriGene • Transient overexpression lysate of alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide (ADH7), transcript variant 2 Validated Antibodies • ADH7 mouse monoclonal antibody,clone 2H10 • ADH7 mouse monoclonal antibody,clone 2D11 • Rabbit polyclonal anti-ADH7 antibody • ADH7 mouse monoclonal antibody,clone 2C3 • Carrier-free (BSA/glycerol-free) ADH7 mouse monoclonal antibody,clone 2C3 • Carrier-free (BSA/glycerol-free) ADH7 mouse monoclonal antibody,clone 2H10 • Carrier-free (BSA/glycerol-free) ADH7 mouse monoclonal antibody,clone 2D11 Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • ADH7 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • ADH7 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Adh7 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • ADH7 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Adh7 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related Primer Pair qSTAR qPCR primer pairs against Homo sapiens gene ADH7

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Protein	Full Length Protein A domain of the protein Description of domain...
Tag	C-fusion N-fusion     Tag Description:
DNA or protein sequence of the final product
Preferred Expression Host	HEK293 E. coli Insect Cells Yeast
The main application with the purified protein	R&D reagent Cell-based Assay Animal Study Other, please specify:
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