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Home Recombinant Human Proteins All RUNX1 Proteins

RUNX1 (NM_001001890) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP323854 Recombinant protein of human runt-related transcription factor 1 (RUNX1), transcript variant 2, 20 ug (Larger pack size?) 680 In Stock
TA307514 Rabbit monoclonal antibody against RUNX1 (clone EPR3099 ) $325 3-7 Days
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Also for RUNX1 (NM_001001890)
cDNA Clone shRNA/siRNA Mass Spec Std Lysate Antibody

OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC223854. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:48.6 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
BioActivity: RUNX1 Activity verified in a DNA-binding assay:
Protein Families: ES Cell Differentiation/IPSTranscription FactorsDruggable Genome
Protein Pathways: Pathways in cancerChronic myeloid leukemiaAcute myeloid leukemia
Protein Data
Protein Image
BioActivity Data
BioActivity Image
 

Reference Data
RefSeq: NP_001001890 RefSeq Size: 7288 RefSeq ORF: 1362
LocusID: 861 Cytogenetic: 21q22.3  
Synonyms : AML1; AML1-EVI-1; AMLCR1; CBFA2; EVI-1; PEBP2aB
Summary: Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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