XDH (NM_000379) Purified Human Protein

Species: Human Expression Host: Human 293HEK cells Expression cDNA Clone and Sequence Recombinant protein was produced with TrueORF clone, RC219402. Click on the TrueORF clone link to view cDNA and protein sequences. Tag: C-terminal MYC/DDK Predicted MW: 146.2 kDa Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining Mass Spec Validation: This protein has been positively validated by MS/MS by Dr. Robert Moritz at The Institute of Systems Biology. Concentration: >50 ug/mL as determined by microplate BCA method Buffer and Storage: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. Protein Families: Druggable Genome Protein Pathways: Purine metabolismCaffeine metabolismDrug metabolism - other enzymesMetabolic pathways

Protein Data

RefSeq: NP_000370	RefSeq Size: 4428	RefSeq ORF: 4002
LocusID: 7498	Cytogenetic: 2p23.1
Synonyms : XO; XOR
Summary: Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The enzyme is a homodimer. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism. [provided by RefSeq, Jul 2008].

Researchers who bought this clone have also purchased:

Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens xanthine dehydrogenase (XDH) as transfection-ready DNA • Lenti ORF clone of Human xanthine dehydrogenase (XDH) , Myc-DDK-tagged • Lenti ORF clone of Human xanthine dehydrogenase (XDH), mGFP tagged • GFP-tagged ORF clone of Homo sapiens xanthine dehydrogenase (XDH) as transfection-ready DNA Related Lysate from OriGene • Transient overexpression lysate of xanthine dehydrogenase (XDH) Validated Antibodies • Anti-Aldolase Mouse Monoclonal Antibody • Rabbit monoclonal antibody against XDH(clone EPR4605) • Rabbit monoclonal antibody against XDH(clone EPR4606) Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • XDH - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • XDH - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Xdh - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • XDH - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Xdh - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related Primer Pair qSTAR qPCR primer pairs against Homo sapiens gene XDH

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Protein	Full Length Protein A domain of the protein Description of domain...
Tag	C-fusion N-fusion     Tag Description:
DNA or protein sequence of the final product
Preferred Expression Host	HEK293 E. coli Insect Cells Yeast
The main application with the purified protein	R&D reagent Cell-based Assay Animal Study Other, please specify:
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