PTGDS (NM_000954) Purified Human Protein

Species: Human Expression Host: Human 293HEK cells Expression cDNA Clone and Sequence Recombinant protein was produced with TrueORF clone, RC216795. Click on the TrueORF clone link to view cDNA and protein sequences. Tag: C-terminal MYC/DDK Predicted MW: 20.8 kDa Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining Mass Spec Validation: This protein has been positively validated by MS/MS by Dr. Robert Moritz at The Institute of Systems Biology. Concentration: >50 ug/mL as determined by microplate BCA method Buffer and Storage: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. Protein Families: Protein Pathways: Arachidonic acid metabolismMetabolic pathways

Protein Data

RefSeq: NP_000945	RefSeq Size: 837	RefSeq ORF: 573
LocusID: 5730	Cytogenetic: 9q34.2
Synonyms : L-PGDS; LPGDS; PDS; PGD2; PGDS; PGDS2
Summary: The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep. [provided by RefSeq, Jul 2008].

Researchers who bought this clone have also purchased:

Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens prostaglandin D2 synthase 21kDa (brain) (PTGDS) as transfection-ready DNA • GFP-tagged ORF clone of Homo sapiens prostaglandin D2 synthase 21kDa (brain) (PTGDS) as transfection-ready DNA • Myc-DDK-tagged ORF clone of Homo sapiens prostaglandin D2 synthase 21kDa (brain) (PTGDS) as 200 ug transfection-ready DNA Related Lysate from OriGene • Transient overexpression lysate of prostaglandin D2 synthase 21kDa (brain) (PTGDS) Validated Antibodies • Rabbit Polyclonal Antibody against PTGDS • Rabbit Polyclonal Antibody against PTGDS Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • PTGDS - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • PTGDS - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Ptgds - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • PTGDS - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Ptgds - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related Primer Pair qSTAR qPCR primer pairs against Homo sapiens gene PTGDS

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Protein	Full Length Protein A domain of the protein Description of domain...
Tag	C-fusion N-fusion     Tag Description:
DNA or protein sequence of the final product
Preferred Expression Host	HEK293 E. coli Insect Cells Yeast
The main application with the purified protein	R&D reagent Cell-based Assay Animal Study Other, please specify:
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