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Home Recombinant Human Proteins All TNNI3 Proteins

TNNI3 (NM_000363) Purified Human Protein

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Cat. No. Description Datasheet Price Availability*  
TP314740 Recombinant protein of human troponin I type 3 (cardiac) (TNNI3), 20 ug (Larger pack size?) $680 In Stock
TA500057 TNNI3 (Cardiac Troponin I) mouse monoclonal antibody, clone OTI4E5 (formerly 4E5) $379 In Stock
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC214740. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:23.8 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: ES Cell Differentiation/IPSStem cell - PluripotencyDruggable Genome
Protein Pathways: Cardiac muscle contractionHypertrophic cardiomyopathy (HCM)Dilated cardiomyopathy
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_000354 RefSeq Size: 2073 RefSeq ORF: 1626
LocusID: 7137 Cytogenetic: 19q13.4  
Synonyms : CMD1FF; CMD2A; CMH7; cTnI; RCM1; TNNC1
Summary: Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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