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Home Recombinant Human Proteins All GLUD1 Proteins

GLUD1 (NM_005271) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP311132 Recombinant protein of human glutamate dehydrogenase 1 (GLUD1), 20 ug (Larger pack size?) $680 In Stock
TA316789 GLUD1 Goat Polyclonal (Internal) Antibody $345 In Stock
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Also for GLUD1 (NM_005271)
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OriGene Data
Species:Human Expression Host:HEK293
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC211132. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:56 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: Druggable Genome
Protein Pathways: Alanine, aspartate and glutamate metabolismArginine and proline metabolismD-Glutamine and D-glutamate metabolismNitrogen metabolismMetabolic pathways
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_005262 RefSeq Size: 3051 RefSeq ORF: 1677
LocusID: 2746 Cytogenetic: 10q23.3  
Synonyms : GDH; GDH1; GLUD
Summary: This gene encodes glutamate dehydrogenase protein; a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid induced insulin secretion and activating mutations in this gene are a common cause of congenital hyperinsulinism. This enzyme is allosterically activated by ADP and inhibited by GTP and ATP. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Multiple pseudogenes of this gene are present in humans.[provided by RefSeq, Sep 2009].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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