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Home Recombinant Human Proteins All ACTC1 Proteins

ACTC1 (NM_005159) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP303655 Recombinant protein of human actin, alpha, cardiac muscle 1 (ACTC1), 20 ug (Larger pack size?) 680
$398
In Stock
TA303378 Rabbit monoclonal antibody against Actin (Pan)(EP184E) $325 In Stock
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Also for ACTC1 (NM_005159)
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC203655. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:41.8 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Mass Spec Validation: This protein has been positively validated by MS/MS by Dr. Robert Moritz at The Institute of Systems Biology.
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Pathways: Cardiac muscle contractionHypertrophic cardiomyopathy (HCM)Dilated cardiomyopathy
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_005150 RefSeq Size: 3693 RefSeq ORF: 1134
LocusID: 70 Cytogenetic: 15q14  
Synonyms : ACTC; ASD5; CMD1R; CMH11; LVNC4
Summary: Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC). [provided by RefSeq, Jul 2008].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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