Promotion ends on May 1st.
Also for MLH1 (NM_000249)
|Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC201607
. Click on the TrueORF clone link to view cDNA and protein sequences.
||Predicted MW:||84.4 kDa|
|Purity:||> 80% as determined by SDS-PAGE and Coomassie blue staining|
|Concentration:||>50 ug/mL as determined by microplate BCA method|
|Buffer:||25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.|
||Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
||Mismatch repairPathways in cancerColorectal cancerEndometrial cancer
||RefSeq Size: 2524
||RefSeq ORF: 2271|
|Synonyms : COCA2; FCC2; hMLH1; HNPCC; HNPCC2|
|Summary: This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.[provided by RefSeq, Nov 2009]. |
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for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich