Promotion ends on May 1st.
Also for OAS1 (NM_002534)
|Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC200696
. Click on the TrueORF clone link to view cDNA and protein sequences.
||Predicted MW:||41.6 kDa|
|Purity:||> 80% as determined by SDS-PAGE and Coomassie blue staining|
|Concentration:||>50 ug/mL as determined by microplate BCA method|
|Buffer:||25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.|
||Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
||RefSeq Size: 1470
||RefSeq ORF: 1095|
|Synonyms : IFI-4; OIAS; OIASI|
|Summary: This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Mutations in this gene have been associated with host susceptibility to viral infection. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]. |
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**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich