OriGene - Purified Protein

OriGene cDNA clones in recent publications

MET Receptor Sequence Variants R970C and T992I Lack Transforming Capacity Cancer Res., Aug 2010; 70: 6233 - 6237 [MET]

Methyl 2-Cyano-3,12-dioxooleana-1,9-dien-28-oate Decreases Specificity Protein Transcription Factors and Inhibits Pancreatic Tumor Growth: Role of MicroRNA-27a Mol. Pharmacol., Aug 2010; 78: 226 - 236 [ZBTB10]

Tumor Lymphangiogenesis and Metastasis to Lymph Nodes Induced by Cancer Cell Expression of Podoplanin Am. J. Pathol., Aug 2010; 177: 1004 - 1016 [PDPN]

AML1 is overexpressed in patients with myeloproliferative neoplasms and mediates JAK2V617F-independent overexpression of NF-E2 Blood, Jul 2010; 116: 254 - 266 [RUNX1]

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5,000 Purified Human Proteins from HEK293 Cells

Powered by extensive collection of TrueORF human cDNA clones, OriGene now offers >5,000 full length human proteins expressed in HEK293 cells and purified with affinity column.

The broadest offering of human proteins produced in human cells

Optimal preservation of protein structure, post-translational modifications and functions

>80% purity through affinity purification

Options for large scale production available.

Applications

Native antigens for optimized antibody production

Positive controls in antibody assays

Standards in ELISA and other assays

Protein-protein interaction

In vitro biochemical assays and cell-based functional assays

Heavy labeled protein as SRM/MRM standards New!

Custom Protein Purification Service

In addition to full length proteins expressed in human HEK293 cells, OriGene offers custom protein expression and purification service to your specific needs, including protein domains, different expression tags, expression host, etc. Please use this custom protein service request form.

Comparison of different protein expression systems

	Mammalian	Yeast	Insect cells	E. coli
Protein folding and purification	Optimal	Poor	Low	Poor
Post-translational processing	Yes	Low	Low	No
Authenticity & Bioactivity	Native and Active	Poor	Poor	Very Poor

Catalog #	Description	Pricing
TPxxxxxx	Affinity purified full length human protein expressed in human HEK293 cells, 20 ug in liquid form	$680

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Technical Support

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