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Home cDNA Clone TrueORF All EPHA8 ORF Clones

EPHA8 (NM_020526) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RC600045 EPHA8 (DDK-His-tagged)-Extra Cellular Domain Clone of Homo sapiens EPH receptor A8, transcript variant 1, Signal peptide (1-27) plus EC domain (28-542), 10µg
In Stock
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Clone Modification
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Also for EPHA8 (NM_020526)
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TrueORF Data for RC600045
Vector: pCMV6-XL5-DDK-His   Change vector? Tag: C-terminal DDK-His
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 1626 bp
Predicted Protein MW: 59.9 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map
OTI Annotation: This clone was engineered to express the extra cellular domain of the protein with an expression tag
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Protein KinaseTransmembraneDruggable Genome
Protein Pathways: Axon guidance

Reference Data
RefSeq: NM_020526.3, NP_065387
RefSeq Size: 4996 RefSeq ORF: 3018
Synonyms : EEK; EK3; HEK3
LocusID: 2046 Cytogenetic: 1p36.12 Domains: pkinase, EPH_lbd, TyrKc, SAM, S_TKc, FN3
Summary: This gene encodes a member of the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. The protein encoded by this gene functions as a receptor for ephrin A2, A3 and A5 and plays a role in short-range contact-mediated axonal guidance during development of the mammalian nervous system. [provided by RefSeq, Jul 2008].


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