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Home cDNA Clone TrueORF All MSRB1 ORF Clones
TrueORF Gold

MSRB1 (NM_016332) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RC201020 MSRB1 (Myc-DDK-tagged)-Human selenoprotein X, 1 (SEPX1), (Note, selenocysteine protein, internal stop codon, see reference data summary), 10µg   
390
$98
In Stock
RG201020 MSRB1 (GFP-tagged) - Human selenoprotein X, 1 (SEPX1), (10ug), (Note: selenocystein protein, Internal stop codon present. See Summary below) $430 In Stock
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Cat. No. Description Price Availability
RC501020 MSRB1 (Myc-DDK-tagged)-Human selenoprotein X, 1 (SEPX1), (200ug) $520 2 weeks
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The same insert cloned in a GFP-tagging vector is also available

Cat. No. Description Vector Price Availability  
RG201020 MSRB1 (GFP-tagged) - Human selenoprotein X, 1 (SEPX1), (10ug), (Note: selenocystein protein, Internal stop codon present. See Summary below)

$430 In Stock
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl Datasheet $248 In Stock
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TrueORF Data for RC201020
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Vector: pCMV6-Entry   Change vector? Tag: C-terminal Myc-DDK
Western validation with an anti-DDK antibody *
L: Control HEK293 lysate
R: Over-expression lysate
Lysate_Image
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 348 bp
Predicted Protein MW: 12.7 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
* The lysates used for this WB picture contain the overexpressed empty vector or the Myc-DDK tagged ORF clone.

Reference Data
RefSeq Explanation: NM_016332.1 NM_016332.2 NM_016332.3 , NP_057416
Synonyms: HSPC270; SELR; SELX; SepR; SEPX1 RefSeq Size: 1386 RefSeq ORF: 351
LocusID: 51734 Cytogenetic: 16p13.3 Domains: SelR
Gene Summary: The protein encoded by this gene belongs to the methionine-R-sulfoxide reductase B (MsrB) family. Members of this family function as repair enzymes that protect proteins from oxidative stress by catalyzing the reduction of methionine-R-sulfoxides to methionines. This protein is highly expressed in liver and kidney, and is localized to the nucleus and cytosol. It is the only member of the MsrB family that is a selenoprotein, containing a selenocysteine (Sec) residue at its active site. It also has the highest methionine-R-sulfoxide reductase activity compared to other members containing cysteine in place of Sec. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. [provided by RefSeq, Oct 2016]

 

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