OriGene Logo
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home cDNA Clone TrueORF All TAX1BP3 ORF Clones
TrueORF Gold

TAX1BP3 (NM_014604) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RC204776 TAX1BP3 (Myc-DDK-tagged)-Human Tax1 (human T-cell leukemia virus type I) binding protein 3 (TAX1BP3), transcript variant 1, 10µg   
390
$98
In Stock
RG204776 TAX1BP3 (GFP-tagged) - Human Tax1 (human T-cell leukemia virus type I) binding protein 3 (TAX1BP3), transcript variant 1 $430 In Stock
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Cat. No. Description Price Availability
RC504776 TAX1BP3 (Myc-DDK-tagged)-Human Tax1 (human T-cell leukemia virus type I) binding protein 3 (TAX1BP3), transcript variant 1, (200ug) $520 2 weeks
Add to Shopping Cart
Clone Modification
spacer

The same insert cloned in a GFP-tagging vector is also available

Cat. No. Description Vector Price Availability  
RG204776 TAX1BP3 (GFP-tagged) - Human Tax1 (human T-cell leukemia virus type I) binding protein 3 (TAX1BP3), transcript variant 1

$430 In Stock
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl Datasheet $248 In Stock
Lenti particle icon Add to Shopping Cart
spacer
TrueORF Data for RC204776
spacer
Vector: pCMV6-Entry   Change vector? Tag: C-terminal Myc-DDK
Western validation with an anti-DDK antibody *
L: Control HEK293 lysate
R: Over-expression lysate
Lysate_Image
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 372 bp
Predicted Protein MW: 13.6 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
* The lysates used for this WB picture contain the overexpressed empty vector or the Myc-DDK tagged ORF clone.

Reference Data
RefSeq Explanation: NM_014604.1 NM_014604.2 NM_014604.3 , NP_055419
Synonyms: TIP-1 RefSeq Size: 1421 RefSeq ORF: 375
LocusID: 30851 Cytogenetic: 17p13.2 Domains: PDZ
Gene Summary: This gene encodes a small, highly conserved protein with a single PDZ domain. PDZ (PSD-95/Discs large/ZO-1 homologous) domains promote protein-protein interactions that affect cell signaling, adhesion, protein scaffolding, and receptor and ion transporter functions. The encoded protein interacts with a large number of target proteins that play roles in signaling pathways; for example, it interacts with Rho A and glutaminase L and also acts as a negative regulator of the Wnt/beta-catenin signaling pathway. This protein was first identified as binding to the T-cell leukaemia virus (HTLV1) Tax oncoprotein. Overexpression of this gene has been implicated in altered cancer cell adhesion, migration and metastasis. The encoded protein also modulates the localization and density of inwardly rectifying potassium channel 2.3 (Kir2.3). To date, this protein has been shown to play a role in cell proliferation, development, stress response, and polarization. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2017]

 

spacer
Inc 5000 Healthcare Company

Notice to Non-US Customers

ExclaimationWeb price and delivery time are for direct sales only.

Non-US customers are encouraged to contact our dedicated distributor network for quotes and streamlined ordering/delivery support.

Acknowledge